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Advanced Search Results For "Humaira Rasheed"

1 - 10 of 113 results for
 "Humaira Rasheed"
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Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Publication Type: Academic Journal

Source(s): Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)

Abstract: A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

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Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Abstract: Identifying causal variants and genes in genome-wide association studies remains a challenge, an issue that is ameliorated with larger sample sizes. Here the authors meta-analyze kidney function genome-wide association studies to identify new loci and ...

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Thermal and spectroscopic studies of some metal complexes with a new enaminone ligand 3-chloro-4-((4-methoxyphenyl)amino)pent-3-en-2-one and their investigation as anti-urease and cytotoxic potential drugs

Publication Type: Academic Journal

Source(s): Arabian Journal of Chemistry, Vol 15, Iss 3, Pp 103640- (2022)

Abstract: Complexes of transition metals [Co(II), Cd(II) and Mo(0)] with a new enaminone (PA) 3-chloro-4-((4-methoxyphenyl)amino)pent-3-en-2-one were synthesized and afterwards characterized by 1H NMR, 13C NMR, FAB-MS, UV–Vis, ICP-OES, TGA and FTIR. The spectros...

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Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study

Publication Type: Academic Journal

Source(s): eLife, Vol 11 (2022)

Abstract: Background: Taller people have a lower risk of coronary heart disease but a higher risk of many cancers. Mendelian randomization (MR) studies in unrelated individuals (population MR) have suggested that these relationships are potentially causal. Howev...

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GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Abstract: Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. Here, the authors conduct a GWAS and suggest protective effect of higher TSH on risk of thyroid cancer and goitre.

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Comparative transcriptomic analysis and endocuticular protein gene expression of alate adults, workers and soldiers of the termite Reticulitermes aculabialis

Publication Type: Academic Journal

Source(s): BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)

Abstract: Abstract Background The insect cuticle is mainly composed of exocuticle and endocuticle layers that consist of a large number of structural proteins. The thickness and synthesis of the exocuticle depend on different castes that perform various function...

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Transcriptome changes reveal the genetic mechanisms of the reproductive plasticity of workers in lower termites

Publication Type: Academic Journal

Source(s): BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)

Abstract: Abstract Background The reproductive plasticity of termite workers provides colonies with tremendous flexibility to respond to environmental changes, which is the basis for evolutionary and ecological success. Although it is known that all colony membe...

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Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout

Publication Type: Academic Journal

Source(s): Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)

Abstract: Abstract Background Some gout-associated loci interact with dietary exposures to influence outcome. The aim of this study was to systematically investigate interactions between alcohol exposure and urate-associated loci in gout. Methods A total of 2792...

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