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Impact of age and comorbidities on SARS-CoV-2 vaccine-induced T cell immunity
Publication Type: Academic Journal
Source(s): Communications Medicine, Vol 3, Iss 1, Pp 1-13 (2023)
Abstract: Abstract Background Older age and chronic disease are important risk factors for developing severe COVID-19. At population level, vaccine-induced immunity substantially reduces the risk of severe COVID-19 disease and hospitalization. However, the relat...
Rationale and design of a prospective, clinical study of kidney biopsies in people with type 2 diabetes and severely increased albuminuria (the PRIMETIME 2 study)
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 13, Iss 6 (2023)
Abstract: Introduction Diabetic kidney disease is a severe complication of diabetes. The diagnosis is based on clinical characteristics such as persistently elevated albuminuria, hypertension and decline in kidney function, although this definition is not specif...
Author Correction: Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Publication Type: Academic Journal
Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)
Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...
Accumulation and diversity of airborne, eukaryotic environmental DNA
Publication Type: Academic Journal
Source(s): Environmental DNA, Vol 4, Iss 6, Pp 1323-1339 (2022)
Abstract: Abstract Environmental DNA (eDNA) metabarcoding is increasingly being implemented as a non‐invasive and efficient approach for biodiversity research and monitoring across ecosystems. However, accurate detection of species with eDNA requires robust expe...
Pigment signatures of algal communities and their implications for glacier surface darkening
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract: Abstract Blooms of pigmented algae darken the surface of glaciers and ice sheets, thereby enhancing solar energy absorption and amplifying ice and snow melt. The impacts of algal pigment and community composition on surface darkening are still poorly u...
Short‐term temporal variation of coastal marine eDNA
Publication Type: Academic Journal
Source(s): Environmental DNA, Vol 4, Iss 4, Pp 747-762 (2022)
Abstract: Abstract Temporal variation in eDNA signals is increasingly explored for understanding community ecology in aquatic habitats. Seasonal changes have been addressed using eDNA sampling, but very little is known regarding short‐term temporal variation tha...
[18F]FE-PE2I PET is a feasible alternative to [123I]FP-CIT SPECT for dopamine transporter imaging in clinically uncertain parkinsonism
Publication Type: Academic Journal
Source(s): EJNMMI Research, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract: Abstract Background Dopamine transporter (DAT) imaging of striatum is clinically used in Parkinson’s disease (PD) and neurodegenerative parkinsonian syndromes (PS) especially in the early disease stages. The aim of the present study was to evaluate the...
Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract: The genetic architecture underlying Sjögren’s syndrome is not fully understood. Here, the authors perform a genome-wide association study to identify 10 new genetic risk regions, implicating genes involved in immune and salivary gland function.
Neurological Complications in COVID-19 Patients: Can Analysis of Specific Antibodies and Viral RNA in Paired Cerebrospinal Fluid and Serum be Used for Accurate Diagnosis of SARS-CoV-2 Neuroinflammatory Disease? A Case Series
Publication Type: Academic Journal
Source(s): Clinical Pathology, Vol 15 (2022)
Abstract: Background: Neurological complications during and after SARS-CoV-2 infection have been frequently described. The detection of either SARS-CoV-2 RNA or specific antibodies against SARS-CoV-2 in cerebrospinal fluid in the context of concomitant neurologi...