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Advanced Search Results For "Johnston, Mara"

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 "Johnston, Mara"
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Eating in a losing cause: limited benefit of modified macronutrient consumption following infection in the oriental cockroach Blatta orientalis

Publication Type: Academic Journal

Source(s): BMC Ecology and Evolution, Vol 22, Iss 1, Pp 1-14 (2022)

Abstract: Abstract Background Host–pathogen interactions can lead to dramatic changes in host feeding behaviour. One aspect of this includes self-medication, where infected individuals consume substances such as toxins or alter their macronutrient consumption to...

2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Abstract: It has been a longstanding goal to promote the propagation of functional mitochondrial DNAs at the expense of pathological molecules in cells where the two species coexist. Here, the authors show that restricting the availability of glucose and glutami...


Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Publication Type: Academic Journal

Source(s): Cell Reports, Vol 35, Iss 13, Pp 109292- (2021)

Abstract: Summary: We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding...

Frequência e caracterização da utilização de cânulas traqueais com balonete em unidades de terapia intensiva neonatais e pediátricas do Brasil

Publication Type: Academic Journal

Source(s): Revista Brasileira de Terapia Intensiva, Vol 32, Iss 2, Pp 235-243 (2020)

Abstract: RESUMO Objetivo: Identificar as unidades de terapia intensiva neonatais, pediátricas e mistas (neonatais e pediátricas) no Brasil que utilizam cânulas traqueais com balonete na prática clínica, e descrever as características relacionadas à utilização d...

Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

Publication Type: Academic Journal

Source(s): The Lancet Public Health, Vol 6, Iss 5, Pp e335-e345 (2021)

Abstract: Summary: Background: The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in England. We aimed to investigate whether increases in the proportion of infections with this variant are associated with differences in symptoms or disease c...

Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 10, Iss 6 (2020)

Abstract: Introduction Ventilator-associated pneumonia (VAP) is a common healthcare-associated infection in the intensive care unit (ICU). Probiotics are defined as live microorganisms that may confer health benefits when ingested. Prior randomised trials sugges...


Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions

Publication Type: Academic Journal

Source(s): JCI Insight, Vol 5, Iss 20 (2020)

Abstract: In the aging population, lower urinary tract (LUT) dysfunction is common and often leads to storage and voiding difficulties classified into overlapping symptom syndromes. Despite prevalence and consequences of these syndromes, LUT disorders continue t...


Extending the Research Data Toolkit: Data Curation Primers

Publication Type: Academic Journal

Source(s): International Journal of Digital Curation, Vol 15, Iss 1 (2020)

Abstract: Niche and proprietary data formats used in cutting-edge research and technology have specific curation considerations and challenges. The increased demand for subject liaisons, library archivists, and digital curators to curate this variety of data typ...

Comparative cytogenetics and derived phylogenic relationship among Sitophilus grain weevils (Coleoptera, Curculionidae, Dryophthorinae)

Publication Type: Academic Journal

Source(s): Comparative Cytogenetics, Vol 12, Iss 2, Pp 223-245 (2018)

Abstract: Cytogenetic characteristics and genome size are powerful tools for species characterization and identification of cryptic species, providing critical insights into phylogenetic and evolutionary relationships. Sitophilus Linnaeus, 1758 grain weevils can...


The potential of shifting recombination hotspots to increase genetic gain in livestock breeding

Publication Type: Academic Journal

Source(s): Genetics Selection Evolution, Vol 49, Iss 1, Pp 1-12 (2017)

Abstract: Abstract Background This study uses simulation to explore and quantify the potential effect of shifting recombination hotspots on genetic gain in livestock breeding programs. Methods We simulated three scenarios that differed in the locations of quanti...