Advanced Search Results For "Jos Philips"
Your filters
α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies
Publication Type: Academic Journal
Source(s): npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract: Abstract There is increasing interest in studying retinal biomarkers for various neurodegenerative diseases. Specific protein aggregates associated with neurodegenerative diseases are present in the retina and could be visualised in a non-invasive way....
Actualizing Human Rights : Global Inequality, Future People, and Motivation
Publication Type: eBook
Abstract: This book argues that ultimately human rights can be actualized, in two senses. By answering important challenges to them, the real-world relevance of human rights can be brought out; and people worldwide can be motivated as needed for realizing human ...
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Abstract: Currently many of the time resolved serial femtosecond (SFX) crystallography experiments are done with light driven protein systems, whereas the reaction initiation for non-light triggered enzymes remains a major bottle neck. Here, the authors present ...
Testing Episodic Memory in Elderly Subjects: Not as Simple as It Looks
Publication Type: Academic Journal
Source(s): Dementia and Geriatric Cognitive Disorders Extra, Vol 9, Iss 2, Pp 207-216 (2019)
Abstract: Background/Aims: The available episodic memory tests are not specifically constructed to examine older subjects. Their use in outpatient memory clinics may result in aborted test administration. We used a strict adherence to the test protocol in cognit...
In-vivo validation of interpolation-based phase offset correction in cardiovascular magnetic resonance flow quantification: a multi-vendor, multi-center study
Publication Type: Academic Journal
Source(s): Journal of Cardiovascular Magnetic Resonance, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract: Abstract Background A velocity offset error in phase contrast cardiovascular magnetic resonance (CMR) imaging is a known problem in clinical assessment of flow volumes in vessels around the heart. Earlier studies have shown that this offset error is cl...
Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+ study
Publication Type: Academic Journal
Source(s): BMC Geriatrics, Vol 18, Iss 1, Pp 1-16 (2018)
Abstract: Abstract Background The oldest-old (subjects aged 90 years and older) population represents the fastest growing segment of society and shows a high dementia prevalence rate of up to 40%. Only a few studies have investigated protective factors for cogni...
Study protocol for a multicentre longitudinal mixed methods study to explore the Outcomes of ChildrEn and fAmilies in the first year after paediatric Intensive Care: the OCEANIC study
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 10, Iss 5 (2020)
Abstract: Introduction Annually in the UK, 20 000 children become very ill or injured and need specialist care within a paediatric intensive care unit (PICU). Most children survive. However, some children and their families may experience problems after they hav...
The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
Publication Type: Academic Journal
Source(s): Ecology and Evolution, Vol 7, Iss 1, Pp 145-188 (2017)
Abstract: Abstract The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (https://www.nhm.ac.uk/our-science/our-work/biodiversity/predicts.html)—has collated from published studies a large, reasonably representative da...
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system
Publication Type: Academic Journal
Source(s): OncoImmunology, Vol 9, Iss 1 (2020)
Abstract: Effective treatment of invasive lobular carcinoma (ILC) of the breast is hampered by late detection, invasive growth, distant metastasis, and poor response to chemotherapy. Phosphoinositide 3-kinase (PI3K) signaling, one of the major druggable oncogeni...
An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group
Publication Type: Academic Journal
Source(s): Frontiers in Neuroinformatics, Vol 12 (2019)
Abstract: Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. Some methodologists claim that a one-stage individual-participant data (IPD) ...