Advanced Search Results For "Kandri Rodi Y"
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QSAR modeling and molecular docking studies of 2-oxo-1, 2-dihydroquinoline-4- carboxylic acid derivatives as p-glycoprotein inhibitors for combating cancer multidrug resistance
Publication Type: Academic Journal
Source(s): Heliyon, Vol 9, Iss 1, Pp e13020- (2023)
Abstract: Multidrug resistance (MDR) proteins related to the ATP-binding cassette family are found in a very wide range of human tumors and result in therapeutic failure. The overexpression of efflux pumps such as ABCB1 is one of the mechanisms of MDR. This pape...
SYNTHESIS, REACTIVITY AND BIOLOGICAL ACTIVITY OF QUINOXALIN-2-ONE DERIVATIVES
Publication Type: Academic Journal
Source(s): Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, Vol 11, Iss 1, Pp 67-90 (2010)
Abstract: Quinoxalines have a great interest in various fields and particularly in chemistry, biology and pharmacology. It enabled the researchers to develop many methods for their preparations and to seek new fields of application. In this review, we’ll expose ...
4-Benzyl-6-bromo-2-(4-methoxyphenyl)-4H-imidazo[4,5-b]pyridine monohydrate
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 4, Pp o947-o947 (2010)
Abstract: The imidazopyridine fused ring in the title compound, C20H16BrN3O·H2O, is coplanar with the aromatic ring at the 2-position [dihedral angle = 5.2 (1)°]. In the five-membered imidazo portion, the C—N bond whose C atom is also connected to the pyridine N...
1,3-Diallyl-5-chloro-1H-benzimidazol-2(3H)-one
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 67, Iss 2, Pp o520-o520 (2011)
Abstract: The benzimidazolone part of the title molecule, C13H13ClN2O, is almost planar (r.m.s. deviation = 0.006 Å) and its mean plane is aligned at dihedral angles of 62.5 (1) and 78.0 (1)° with respect to the mean planes of the allyl substituents.
1,3-Dibenzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 4, Pp o754-o754 (2010)
Abstract: The imidazopyridine fused-ring in the title compound, C20H16BrN3O, is planar (r.m.s. deviation = 0.011 Å). The phenyl rings of the benzyl substitutents twist away from the central five-membered ring in opposite directions; the rings are aligned at 61.3...
3-[(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl]-1,5-dimethyl-1,5-benzodiazepine-2,4-dione
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 3, Pp o632-o632 (2010)
Abstract: The title compound, C21H21N5O2, is a 1,4-dimethyl-1,2,3-triazole having dimethylbenzodiazepindione and phenyl substituents on each methyl group; the substituents are positioned on opposite sides of the five-membered ring. The seven-membered fused-ring ...
3-[(1-Benzyl-1H-1,2,3-triazol-5-yl)methyl]-1,5-dimethyl-1,5-benzodiazepine-2,4-dione monohydrate
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 3, Pp o633-o633 (2010)
Abstract: In the title compound, C21H21N5O2·H2O, the seven-membered ring adopts a boat-shaped conformation with the methine C atom as the prow. In the crystal, the water molecule links adjacent molecules by O—H...O and O—H...N hydrogen bonds into a zigzag chain ...
6-Bromo-1-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-1H-imidazo[4,5-b]pyridin-2(3H)-one
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 2, Pp o456-o456 (2010)
Abstract: The title compound, C11H11BrN4O3, features an ethane fragment substituted with an almost planar (r.m.s. deviation = 0.019 Å) imidazo[4,5-b]pyridone ring system and an envelope-shaped oxazolidine unit on separate C atoms. The N—CH2—CH2—N torsion angle i...
Ethyl 2-{4-[(1,5-dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 66, Iss 1, Pp o126-o126 (2010)
Abstract: The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with ethyl azidoacetate in the presence of copper sulfate pentahydrate and sodium ascorbate leads to the formation of the title regioisomer, C30H29N5O4, which features a phenylene ri...
3-Allyl-1,5-dibenzyl-1,5-benzodiazepine-2,4-dione
Publication Type: Academic Journal
Source(s): Acta Crystallographica Section E, Vol 65, Iss 12, Pp o3150-o3150 (2009)
Abstract: The title compound, C26H24N2O2, features a benzene ring fused with a seven-membered diazepine ring; the latter ring adopts a boat conformation (with the allyldimethylaminomethyl-bearing C atom as the prow and the fused-ring C atoms as the stern).