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    • Outcome of severely injured patients in a unique trauma system with 24/7 double trauma surgeon on-call service

    Publication Type: Academic Journal

    Source(s): Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 31, Iss 1, Pp 1-13 (2023)

    Abstract: Abstract Background The presence of in-house attending trauma surgeons has improved efficiency of processes in the treatment of polytrauma patients. However, literature remains equivocal regarding the influence of the presence of in-house attendings on...

    Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice

    Publication Type: Academic Journal

    Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

    Abstract: Abstract The initial steps of B-cell acute lymphoblastic leukemia (B-ALL) development usually pass unnoticed in children. Several preclinical studies have shown that exposure to immune stressors triggers the transformation of preleukemic B cells to ful...

    Subjects:

    Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures

    Publication Type: Academic Journal

    Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

    Abstract: Abstract Plasmodium falciparum (Pf) parasite development in liver represents the initial step of the life-cycle in the human host after a Pf-infected mosquito bite. While an attractive stage for life-cycle interruption, understanding of parasite-hepato...

    Subjects:

    Problem based learning and design thinking methodologies for teaching renewable energy in engineering programs: Implementation in a Colombian university context

    Publication Type: Academic Journal

    Source(s): Cogent Engineering, Vol 10, Iss 1 (2023)

    Abstract: AbstractThe rapid depletion of fossil fuel reserves, population growth, and increasing environmental pollution have forced a change in the search for alternatives to produce and use energy. Currently, renewable energies (RE) have achieved more efficien...

    Germline landscape of RPA1, RPA2 and RPA3 variants in pediatric malignancies: identification of RPA1 as a novel cancer predisposition candidate gene

    Publication Type: Academic Journal

    Source(s): Frontiers in Oncology, Vol 13 (2023)

    Abstract: Replication Protein A (RPA) is single-strand DNA binding protein that plays a key role in the replication and repair of DNA. RPA is a heterotrimer made of 3 subunits – RPA1, RPA2, and RPA3. Germline pathogenic variants affecting RPA1 were recently desc...

    A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects

    Publication Type: Academic Journal

    Source(s): Drug Design, Development and Therapy, Vol Volume 17, Pp 1203-1210 (2023)

    Authors:

    Abstract: Hyun Chul Kim,1,2 Sangmi Lee,1,2 Siyoung Sung,3 Eunjin Kim,3 In-Jin Jang,1 Jae-Yong Chung4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; 2Integrated Major in...

    Susceptibility antibiotic screening reveals high rates of multidrug resistance of Salmonella, Shigella and Campylobacter in HIV infected and uninfected patients from Mozambique

    Publication Type: Academic Journal

    Source(s): BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-8 (2023)

    Abstract: Abstract Background Antibacterial resistance is a growing concern worldwide, including in Mozambique. Diarrhea is an important cause of mortality in Mozambique, yet few local studies have reported on the resistance of bacterial pathogens in this contex...

    A framework for community curation of interspecies interactions literature

    Publication Type: Academic Journal

    Source(s): eLife, Vol 12 (2023)

    Abstract: The quantity and complexity of data being generated and published in biology has increased substantially, but few methods exist for capturing knowledge about phenotypes derived from molecular interactions between diverse groups of species, in such a wa...

    Efficacy, Safety and Cost-Effectiveness of Thread-Embedding Acupuncture for Adhesive Capsulitis (Frozen Shoulder): A Study Protocol for a Multicenter, Randomized, Patient-Assessor Blinded, Controlled Trial

    Publication Type: Academic Journal

    Source(s): Journal of Pain Research, Vol Volume 16, Pp 623-633 (2023)

    Authors:

    Abstract: Bonhyuk Goo,1,* Yeon-Cheol Park,2,* Eunseok Kim,3,4 Won-Suk Sung,5 Eun-Jung Kim,6 Jung-Hyun Kim,1 Byung-Kwan Seo,2 Yong-Hyeon Baek2 1Department of Acupuncture & Moxibustion, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea; 2...

    S107: IDENTIFICATION AND CHARACTERIZATION OF GERMLINE NBN VARIANTS RELATED TO B-ALL PREDISPOSITION

    Publication Type: Academic Journal

    Source(s): HemaSphere, Vol 7, p e4470514 (2023)

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