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Advanced Search Results For "Korn, Michael"

1 - 10 of 910 results for
 "Korn, Michael"
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Association of the retinal vasculature, intrathecal immunity, and disability in multiple sclerosis

Publication Type: Academic Journal

Source(s): Frontiers in Immunology, Vol 13 (2022)

Abstract: BackgroundOptical coherence tomography angiography (OCT-A) is a novel technique allowing non-invasive assessment of the retinal vasculature. During relapsing remitting multiple sclerosis (RRMS), retinal vessel loss occurs in eyes suffering from acute o...

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Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant

Publication Type: Academic Journal

Source(s): BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In November 2021, the Omicron variant was discovered and immediately classified as a variant of concern (VOC), since it shows substantially more mutations in the spi...

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Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic

Publication Type: Academic Journal

Source(s): Critical Care Explorations, Vol 4, Iss 4, p e0686 (2022)

Abstract: OBJECTIVES:. To describe the prevalence, associated risk factors, and outcomes of serious neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) among patients hospitalized with severe acute respiratory syndrome corona...

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Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients

Publication Type: Academic Journal

Source(s): npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)

Abstract: Abstract Lymph nodes (LNs) and distant metastases can arise from independent subclones of the primary tumor. Herein, we characterized the molecular landscape and the differences between LNs, distant metastases and primary colorectal cancers (CRCs). Sam...

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Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling

Publication Type: Academic Journal

Source(s): BMC Neurology, Vol 21, Iss 1, Pp 1-13 (2021)

Abstract: Abstract Background Gliosarcoma (GS) refers to the presence of mesenchymal differentiation (as seen using light microscopy) in the setting of glioblastoma (GB, an astrocytoma, WHO Grade 4). Although the same approach to treatment is typically adopted f...

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Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County—Results from a Population-Based Longitudinal Study in Germany

Publication Type: Academic Journal

Source(s): Viruses, Vol 14, Iss 1168, p 1168 (2022)

Abstract: Herein, we provide results from a prospective population-based longitudinal follow-up (FU) SARS-CoV-2 serosurveillance study in Tirschenreuth, the county which was hit hardest in Germany in spring 2020 and early 2021. Of 4203 individuals aged 14 years ...

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Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

Abstract: Abstract Patients with cancer demonstrate particularly poor outcomes from COVID-19. To provide information essential for understanding the biologic underpinnings of this association, we analyzed whole-transcriptome RNA expression data obtained from a l...

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Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

Publication Type: Academic Journal

Source(s): Critical Care Explorations, Vol 3, Iss 8, p e0514 (2021)

Abstract: IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology ...

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Transcriptional Profiling of Malignant Melanoma Reveals Novel and Potentially Targetable Gene Fusions

Publication Type: Academic Journal

Source(s): Cancers, Vol 14, Iss 1505, p 1505 (2022)

Abstract: Invasive melanoma is the deadliest type of skin cancer, with 101,110 expected cases to be diagnosed in 2021. Recurrent BRAF and NRAS mutations are well documented in melanoma. Biologic implications of gene fusions and the efficacy of therapeutically ta...

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Baculovirus-free insect cell expression system for high yield antibody and antigen production

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

Abstract: Abstract Antibodies are essential tools for therapy and diagnostics. Yet, production remains expensive as it is mostly done in mammalian expression systems. As most therapeutic IgG require mammalian glycosylation to interact with the human immune syste...

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