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Advanced Search Results For "LOVE, KATHERINE"

1 - 10 of 454 results for
 "LOVE, KATHERINE"
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Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases

Publication Type:Academic Journal

Source(s):npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)

Abstract:Abstract TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 classif...

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RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge

Publication Type:Academic Journal

Source(s):mSphere, Vol 7, Iss 4 (2022)

Abstract:ABSTRACT The ongoing COVID-19 pandemic has contributed largely to the global vaccine disparity. Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines delivered to low-income countries. Here, we evaluated the efficacy...

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Race and sex differences in HDL peroxide content among American adults with and without type 2 diabetes

Publication Type:Academic Journal

Source(s):Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-12 (2022)

Abstract:Abstract Background High-density lipoprotein (HDL) plays a critical role in protection against atherosclerosic and cardiovascular disease (ASCVD). In addition to contributing to clearing excess vascular cholesterol, HDL particles exhibit antioxidative ...

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DNA Damage Repair Classifier Defines Distinct Groups in Hepatocellular Carcinoma

Publication Type:Academic Journal

Source(s):Cancers, Vol 14, Iss 4282, p 4282 (2022)

Abstract:DNA repair pathways have been associated with variability in hepatocellular carcinoma (HCC) clinical outcomes, but the mechanism through which DNA repair varies as a function of liver regeneration and other HCC characteristics is poorly understood. We ...

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Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic

Publication Type:Academic Journal

Source(s):Critical Care Explorations, Vol 4, Iss 4, p e0686 (2022)

Abstract:OBJECTIVES:. To describe the prevalence, associated risk factors, and outcomes of serious neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) among patients hospitalized with severe acute respiratory syndrome corona...

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Hepatocyte growth factor pathway expression in breast cancer by race and subtype

Publication Type:Academic Journal

Source(s):Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)

Abstract:Abstract Background African American women have the highest risk of breast cancer mortality compared to other racial groups. Differences in tumor characteristics have been implicated as a possible cause; however, the tumor microenvironment may also con...

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Outcomes in reported penicillin allergic mothers and neonates requiring Group B streptococcal prophylaxis: a retrospective observational cohort study

Publication Type:Academic Journal

Source(s):BMC Pediatrics, Vol 21, Iss 1, Pp 1-7 (2021)

Abstract:Abstract Background Infectious morbidity and mortality in the first week of life is commonly caused by early-onset neonatal Group B streptococcus (GBS) disease. This infection is spread from GBS positive mothers to neonates by vertical transmission dur...

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Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

Publication Type:Academic Journal

Source(s):Critical Care Explorations, Vol 3, Iss 8, p e0514 (2021)

Abstract:IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology ...

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SCISSOR: a framework for identifying structural changes in RNA transcripts

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Abstract:Many computational tools identify mRNA variations by analyzing the transformed RNA-seq data such as collapsed reads. Here, the authors report a computational method which uses shape changes in the RNA-seq coverage profile to discover changes in mRNA ex...

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The role of endometrial sampling for surveillance of recurrence in postmenopausal patients with medically inoperable stage I endometrial cancer

Publication Type:Academic Journal

Source(s):Gynecologic Oncology Reports, Vol 35, Iss , Pp 100694- (2021)

Abstract:It is unclear if surveillance for postmenopausal women with medically inoperable stage 1 endometrial cancer (EC) should differ depending on their management strategy. Thus, we investigated the utility of surveillance endometrial sampling among 53 postm...

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