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A continuous 4D motion model from multiple respiratory cycles for use in lung radiotherapy.
Publication Type: Academic Journal
Source(s): Medical Physics; Sep2006, Vol. 33 Issue 9, p3348-3358, 11p
Ruminant self-medication against gastrointestinal nematodes: evidence, mechanism, and origins☆
Publication Type: Academic Journal
Source(s): Parasite, Vol 21, p 31 (2014)
Abstract: Gastrointestinal helminths challenge ruminants in ways that reduce their fitness. In turn, ruminants have evolved physiological and behavioral adaptations that counteract this challenge. Ruminants display anorexia and avoidance behaviors, which tend to...
Chemical Mixtures and Multiple Stressors: Same but Different?
Publication Type: Academic Journal
Source(s): Environmental toxicology and chemistry [Environ Toxicol Chem] 2023 Sep; Vol. 42 (9), pp. 1915-1936. Date of Electronic Publication: 2023 May 17.
Abstract: Ecosystems are strongly influenced by multiple anthropogenic stressors, including a wide range of chemicals and their mixtures. Studies on the effects of multiple stressors have largely focussed on nonchemical stressors, whereas studies on chemical mix...
Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Publication Type: Academic Journal
Source(s): Archives of toxicology [Arch Toxicol] 2023 Nov; Vol. 97 (11), pp. 2903-2917. Date of Electronic Publication: 2023 Sep 04.
Abstract: Omics techniques have been increasingly recognized as promising tools for Next Generation Risk Assessment. Targeted metabolomics offer the advantage of providing readily interpretable mechanistic information about perturbed biological pathways. In this...
A high-throughput metabolomics in vitro platform for the characterization of hepatotoxicity.
Publication Type: Academic Journal
Source(s): Cell biology and toxicology [Cell Biol Toxicol] 2023 May 04. Date of Electronic Publication: 2023 May 04.
Abstract: Cell-based metabolomics provides multiparametric physiologically relevant readouts that can be highly advantageous for improved, biologically based decision making in early stages of compound development. Here, we present the development of a 96-well p...
Cascading impacts of changes in subsidy quality on recipient ecosystem functioning.
Publication Type: Academic Journal
Source(s): Ecology [Ecology] 2023 May; Vol. 104 (5), pp. e4023. Date of Electronic Publication: 2023 Mar 27.
Abstract: Resource quantity and quality can differ between adjacent ecosystems, and these differences can impact subsidies exchanged between ecosystems. The quantity and quality of subsidies are rapidly changing in response to stressors associated with global en...
The ectonucleotidase CD39 identifies tumor-reactive CD8 + T cells predictive of immune checkpoint blockade efficacy in human lung cancer.
Publication Type: Academic Journal
Source(s): Immunity [Immunity] 2023 Jan 10; Vol. 56 (1), pp. 93-106.e6. Date of Electronic Publication: 2022 Dec 26.
Abstract: Improved identification of anti-tumor T cells is needed to advance cancer immunotherapies. CD39 expression is a promising surrogate of tumor-reactive CD8 + T cells. Here, we comprehensively profiled CD39 expression in human lung cancer. CD39 expression...
The Cryo-EM structures of two amphibian antimicrobial cross-β amyloid fibrils.
Publication Type: Academic Journal
Source(s): Nature communications [Nat Commun] 2022 Jul 27; Vol. 13 (1), pp. 4356. Date of Electronic Publication: 2022 Jul 27.
Abstract: The amyloid-antimicrobial link hypothesis is based on antimicrobial properties found in human amyloids involved in neurodegenerative and systemic diseases, along with amyloidal structural properties found in antimicrobial peptides (AMPs). Supporting th...
How social rejection expectations and depressive symptoms bi-directionally predict each other - A cross-lagged panel analysis.
Publication Type: Academic Journal
Source(s): Psychology and psychotherapy [Psychol Psychother] 2022 Jun; Vol. 95 (2), pp. 477-492. Date of Electronic Publication: 2022 Jan 31.
Abstract: Background: Although research suggests that social rejection expectations play a crucial role in the development and maintenance of depressive symptoms, it is not clear whether such expectations are a risk factor for depression or rather a consequence ...
Distribution and Relative Abundance of Bean Leaf Beetles ( Ootheca spp.) (Insecta: Coleoptera: Chrysomelidae) in Uganda.
Publication Type: Academic Journal
Source(s): Insects [Insects] 2021 Nov 22; Vol. 12 (11). Date of Electronic Publication: 2021 Nov 22.
Abstract: Bean leaf beetles ( Ootheca spp.) (Insecta: Coleoptera: Chrysomelidae) are one of Africa's most destructive pests of common bean and other leguminous crops. The beetles are widely distributed in Africa where they are estimated to cause annual crop yiel...