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Advanced Search Results For "Lei, Xia"

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 "Lei, Xia"
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Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy

Publication Type:Academic Journal

Source(s):Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-28 (2022)

Abstract:Abstract Light-mediated nanotherapeutics have recently emerged as promising strategies to precisely control the activation of therapeutic reagents and imaging probe both in vitro and in vivo, largely ascribed to their unique properties, including minim...

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Elevated air quality index and fine particulate matter levels contribute to the poor prognosis and progression of nonsmall‐cell lung cancer: A cohort study combined with external validation

Publication Type:Academic Journal

Source(s):Cancer Medicine, Vol 11, Iss 17, Pp 3272-3281 (2022)

Abstract:Abstract Background Poor air quality can result in a variety of respiratory disorders. However, the air quality index (AQI) and the level of fine particulate matter (PM2.5) on the progression and prognosis of nonsmall‐cell lung cancer (NSCLC) are uncle...

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m6A-induced repression of SIAH1 facilitates alternative splicing of androgen receptor variant 7 by regulating CPSF1

Publication Type:Academic Journal

Source(s):Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 219-230 (2022)

Abstract:Androgen receptor splice variant 7 (AR-v7), a constitutively active transcription factor, plays a crucial role in the progression of castration-resistant prostate cancer (CRPC). Here, we found that the cleavage and polyadenylation specificity factor 1 ...

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Molecular mechanism of lncRNA SNHG12 in immune escape of non-small cell lung cancer through the HuR/PD-L1/USP8 axis

Publication Type:Academic Journal

Source(s):Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-23 (2022)

Abstract:Abstract Background The pivotal role of long noncoding RNAs (lncRNAs) in cancer immune responses has been well established. This study was conducted with the aim of exploring the molecular mechanism of lncRNA small nucleolar RNA host gene 12 (SNHG12) i...

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Investigating the influence of breastfeeding on asthma in children under 12 years old in the UK Biobank

Publication Type:Academic Journal

Source(s):Frontiers in Immunology, Vol 13 (2022)

Abstract:BackgroundChildhood-onset asthma (COA) has become a major and growing problem worldwide and imposes a heavy socioeconomic burden on individuals and families; therefore, understanding the influence of early-life experiences such as breastfeeding on COA ...

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A Chinese classical prescription Guizhi-Fuling Wan in treatment of ovarian cancer: An overview

Publication Type:Academic Journal

Source(s):Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113401- (2022)

Abstract:Ovarian cancer is one of the three most common female reproductive system cancers and has been a hot topic in the field of gynecology and oncology. Currently, surgery with chemotherapy is the common strategy in treatment of ovarian cancer, while it is ...

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Association of higher plasma leptin levels with HOMA-IR index, high sensitivity C-reactive protein and glycolipid metabolism in patients with chronic schizophrenia: A multi-center cross-sectional study

Publication Type:Academic Journal

Source(s):Frontiers in Psychiatry, Vol 13 (2022)

Abstract:BackgroundPrevious research has revealed that plasma leptin levels were closely related to glycolipid metabolism in schizophrenic patients. Insulin resistance (IR) and high sensitivity C-reactive protein (hs-CRP) were involved in glucolipid metabolism ...

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Progress on structural modification of Tetrandrine with wide range of pharmacological activities

Publication Type:Academic Journal

Source(s):Frontiers in Pharmacology, Vol 13 (2022)

Abstract:Tetrandrine (Tet), derived from the traditional Chinese herb Fangji, is a class of natural alkaloids with the structure of bisbenzylisoquinoline, which has a wide range of physiological activities and significant pharmacfological effects. However, stud...

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Research progress on classical traditional Chinese medicine Taohong Siwu decoction in the treatment of coronary heart disease

Publication Type:Academic Journal

Source(s):Biomedicine & Pharmacotherapy, Vol 152, Iss , Pp 113249- (2022)

Abstract:The pathogenesis of coronary heart disease is closely related to blood stasis. Taohong Siwu decoction (THSW for short) is one of the most widely used prescriptions for activating blood and removing stasis. Clinical research has confirmed its curative e...

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Co‐occurrence of CDKN2A/B and IFN‐I homozygous deletions correlates with an immunosuppressive phenotype and poor prognosis in lung adenocarcinoma

Publication Type:Academic Journal

Source(s):Molecular Oncology, Vol 16, Iss 8, Pp 1746-1760 (2022)

Abstract:Homozygous deletion (HD) of CDKN2A and CDKN2B (CDKN2A/BHD) is the most frequent copy‐number variation (CNV) in lung adenocarcinoma (LUAD). CDKN2A/BHD has been associated with poor outcomes in LUAD; however, the mechanisms of its prognostic effect remai...

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