Advanced Search Results For "Leong DT"
Your filters
Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non-Small-Cell Lung Cancer in Asia (IPASS)
Publication Type: Academic Journal
Source(s): Journal of Clinical Oncology; 7/20/2011, Vol. 29 Issue 21, p2866-2874, 9p
Effective breast reconstruction in female veterans.
Publication Type: Academic Journal
Source(s): American Journal of Surgery. Nov2009 Supplement, Vol. 198 Issue 5, p658-663. 6p.
Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours.
Publication Type: Academic Journal
Source(s): Nature nanotechnology [Nat Nanotechnol] 2023 Sep 14. Date of Electronic Publication: 2023 Sep 14.
Abstract: An effective nanotherapeutic transport from the vasculature to the tumour is crucial for cancer treatment with minimal side effects. Here we demonstrate that, in addition to the endothelial barrier, the tumour vascular basement membrane surrounding the...
Universal DNA methylation age across mammalian tissues.
Publication Type: Academic Journal
Source(s): Nature aging [Nat Aging] 2023 Sep; Vol. 3 (9), pp. 1144-1166. Date of Electronic Publication: 2023 Aug 10.
Abstract: Aging, often considered a result of random cellular damage, can be accurately estimated using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we demonstrate the development of universal pan-mammalian clocks, using 11,754...
Real-world practice of Helicobacter pylori management: A survey among physicians in Southeast Asia.
Publication Type: Academic Journal
Source(s): Helicobacter [Helicobacter] 2023 Aug 27, pp. e13018. Date of Electronic Publication: 2023 Aug 27.
Abstract: Background: Multidrug-resistant Helicobacter pylori strains are emerging in Southeast Asia. This study evaluates the region's real-world practice in H. pylori management.Materials and Methods: Physicians who managed H. pylori eradication in daily pract...
DNA methylation networks underlying mammalian traits.
Publication Type: Academic Journal
Source(s): Science (New York, N.Y.) [Science] 2023 Aug 11; Vol. 381 (6658), pp. eabq5693. Date of Electronic Publication: 2023 Aug 11.
Abstract: Using DNA methylation profiles ( n = 15,456) from 348 mammalian species, we constructed phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using unsupervised clustering across all samples, we identified 55 distinct cy...
Native Mass Spectrometry Quantitation of α2-3-Linked N -Acetylneuraminic Acid Content of Prostate-Specific Antigen: An Accurate Liquid Biopsy for Clinically Significant Prostate Cancer.
Publication Type: Academic Journal
Source(s): Analytical chemistry [Anal Chem] 2023 Jul 25; Vol. 95 (29), pp. 10903-10912. Date of Electronic Publication: 2023 Jul 13.
Abstract: Application of the prostate-specific antigen (PSA) test, which measures PSA levels in blood, is standard in prostate cancer (PCa) screening. However, because PSA levels may be elevated for reasons other than PCa, it leads to high rates of misdiagnosis ...
Engineering tumoral vascular leakiness with gold nanoparticles.
Publication Type: Academic Journal
Source(s): Nature communications [Nat Commun] 2023 Jul 17; Vol. 14 (1), pp. 4269. Date of Electronic Publication: 2023 Jul 17.
Abstract: Delivering cancer therapeutics to tumors necessitates their escape from the surrounding blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer therapeutically competent leakage of therapeutics from tumor vasculature wi...