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Non-carrier nanoparticles adjuvant modular protein vaccine in a particle-dependent manner.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 10, Iss 3, p e0117203 (2015)
Abstract: Nanoparticles are increasingly used to adjuvant vaccine formulations due to their biocompatibility, ease of manufacture and the opportunity to tailor their size, shape, and physicochemical properties. The efficacy of similarly-sized silica (Si-OH), pol...
Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 9, Iss 9, p e107313 (2014)
Abstract: The success of recombinant virus-like particles (VLPs) for human papillomavirus and hepatitis B demonstrates the potential of VLPs as safe and efficacious vaccines. With new modular designs emerging, the effects of antigen module insertion on the self-...
Differential effects of collagen prolyl 3-hydroxylation on skeletal tissues.
Publication Type: Academic Journal
Source(s): PLoS Genetics, Vol 10, Iss 1, p e1004121 (2014)
Abstract: Mutations in the genes encoding cartilage associated protein (CRTAP) and prolyl 3-hydroxylase 1 (P3H1 encoded by LEPRE1) were the first identified causes of recessive Osteogenesis Imperfecta (OI). These proteins, together with cyclophilin B (encoded by...
Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8+ T Cell and Antibody Responses
Publication Type: Academic Journal
Source(s): Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Abstract: An effective vaccine against the Plasmodium parasite is likely to require the induction of robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine platform for induction of antibody responses, but their capacity to ...
Insert engineering and solubility screening improves recovery of virus-like particle subunits displaying hydrophobic epitopes.
Publication Type: Academic Journal
Source(s): Protein Science: A Publication of the Protein Society; Nov2015, Vol. 24 Issue 11, p1820-1828, 9p
Abstract: Copyright of Protein Science: A Publication of the Protein Society is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. Howe...
Encapsulation of DNA and non-viral protein changes the structure of murine polyomavirus virus-like particles.
Publication Type: Academic Journal
Source(s): Archives of Virology; Nov2008, Vol. 153 Issue 11, p2027-2039, 13p, 2 Black and White Photographs, 4 Diagrams, 1 Chart, 1 Graph
Abstract: Copyright of Archives of Virology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, o...
Design and optimization of membrane chromatography for monoclonal antibody charge variant separation.
Publication Type: Academic Journal
Source(s): Biotechnology Progress; Nov2022, Vol. 38 Issue 6, p1-15, 15p
Abstract: Copyright of Biotechnology Progress is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download,...
Ambient Temperature Stable, Scalable COVID‐19 Polymer Particle Vaccines Induce Protective Immunity.
Publication Type: Academic Journal
Source(s): Advanced Healthcare Materials; Feb2022, Vol. 11 Issue 3, p1-14, 14p
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases.
Publication Type: Academic Journal
Source(s): Nature Protocols; Mar2021, Vol. 16 Issue 3, p1740-1760, 21p
Intensified Downstream Processing of Monoclonal Antibodies Using Membrane Technology.
Publication Type: Academic Journal
Source(s): Biotechnology Journal; Mar2021, Vol. 16 Issue 3, p1-11, 11p