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Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract: Microglia are important for brain homeostasis and plasticity. The mechanisms underlying microglia-neuron interactions are still unclear. Here, the authors show that microglia preferentially interact with the nodes of Ranvier along axons. This interacti...
Physiopathologie de la sclérose en plaques : actualités
Publication Type: Periodical
Source(s): Bulletin de l'Académie Nationale de Médecine; June 2022, Vol. 206 Issue: 6 p721-726, 6p
Abstract: La sclérose en plaques est une maladie inflammatoire du système nerveux central, dont le déclenchement est favorisé par des facteurs génétiques et environnementaux. Le point de départ du processus pathologique (en périphérie ou dans le système nerveux ...
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain
Publication Type: Academic Journal
Source(s): eLife, Vol 6 (2017)
Abstract: In the adult brain, both neurons and oligodendrocytes can be generated from neural stem cells located within the Sub-Ventricular Zone (SVZ). Physiological signals regulating neuronal versus glial fate are largely unknown. Here we report that a thyroid ...
Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination.
Publication Type: Academic Journal
Source(s): Nature Communications; 9/1/2021, Vol. 12 Issue 1, p1-18, 18p
Abstract: Copyright of Nature Communications is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, ...
Patterns of Objective and Subjective Burden of Informal Caregivers in Multiple Sclerosis
Publication Type: Academic Journal
Source(s): Behavioural Neurology, Vol 2015 (2015)
Abstract: Background. Home care for patients with Multiple Sclerosis (MS) relies largely on informal caregivers (ICs). Methods. We assessed ICs objective burden (Resource Utilization in Dementia measuring informal care time (ICT)) and ICs subjective burden (Zari...
A comparative evaluation of different neuromyelitis optica spectrum disorder sets of criteria.
Publication Type: Academic Journal
Source(s): European Journal of Neurology; Nov2020, Vol. 27 Issue 11, p2250-2256, 7p
Abstract: Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, do...
New OFSEP recommendations for MRI assessment of multiple sclerosis patients: Special consideration for gadolinium deposition and frequent acquisitions
Publication Type: Periodical
Source(s): Journal de Neuroradiologie / Journal of Neuroradiology; June 2020, Vol. 47 Issue: 4 p250-258, 9p
Abstract: New multiple sclerosis (MS) disease-modifying therapies (DMTs), which exert beneficial effects through prevention of relapse, limitation of disability progression, and improvement of patients’ quality of life, have recently emerged. Nonetheless, these ...
The cerebrospinal fluid CD4/CD8 ratio and interleukin‐6 and ‐10 levels in neurosarcoidosis: a multicenter, pragmatic, comparative study.
Publication Type: Academic Journal
Source(s): European Journal of Neurology; Oct2019, Vol. 26 Issue 10, p1274-1280, 7p, 1 Black and White Photograph, 2 Charts, 2 Graphs
Abstract: Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, do...
Spécificités de la sclérose en plaques chez les Maghrébins : rôle des facteurs environnementaux et génétiques
Publication Type: Periodical
Source(s): Bulletin de l'Académie Nationale de Médecine; April 2020, Vol. 204 Issue: 4 p421-427, 7p
Abstract: La sclérose en plaques est une maladie inflammatoire chronique du système nerveux central d’étiologie auto-immune. Son phénotype et son évolution peuvent différer d’un patient à l’autre. L’épidémiologie et la présentation de la sclérose en plaques ont ...
Immunization and multiple sclerosis: Recommendations from the French Multiple Sclerosis Society
Publication Type: Periodical
Source(s): Revue Neurologique; June 2019, Vol. 175 Issue: 6 p341-357, 17p
Abstract: To establish recommendations on immunization for patients with multiple sclerosis (MS).