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Advanced Search Results For "MITCHELL, GAIL"

1 - 10 of 7,109 results for
 "MITCHELL, GAIL"
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Spline Analysis of Biomarker Data Pooled from Multiple Matched/Nested Case–Control Studies

Publication Type: Academic Journal

Source(s): Cancers, Vol 14, Iss 2783, p 2783 (2022)

Abstract: Pooling biomarker data across multiple studies enables researchers to obtain precise estimates of the association between biomarker measurements and disease risks due to increased sample sizes. However, biomarker measurements often vary significantly a...

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Estimating vaccine effectiveness against SARS-CoV-2 infection, hospitalization and death from ecologic data in Costa Rica

Publication Type: Academic Journal

Source(s): BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background Clinical trials and individual-level observational data in Israel demonstrated approximately 95% effectiveness of mRNA-based vaccines against symptomatic SARS-CoV-2 infection. Individual-level data are not available in many countrie...

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OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract: Abstract Androgen and androgen receptor (AR) targeted therapies are the main treatment for most prostate cancer (PC) patients. Although AR signaling inhibitors are effective, tumors can evade this treatment by transforming to an AR-negative PC via line...

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Evaluation of serological assays for SARS-CoV-2 antibody testing from dried blood spots collected from cohorts with prior SARS-CoV-2 infection

Publication Type: Academic Journal

Source(s): Journal of Clinical Virology Plus, Vol 2, Iss 3, Pp 100093- (2022)

Abstract: Background: Dried blood spot (DBS) specimens are a useful serosurveillance tool particularly in hard-to-reach populations but their application for detecting SARS-CoV-2 infection is poorly characterised. Objectives: To compare detection of naturally ac...

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Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

Publication Type: Academic Journal

Source(s): The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)

Abstract: Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...

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The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Abstract: The prognosis of castration-resistant prostate cancers remains dismal, but accurate preclinical models can lead to effective therapies. Here the Melbourne Urological Research Alliance establish prostate cancer patient-derived xenografts, use the tumors...

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Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Abstract: The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type: Academic Journal

Source(s): iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract: Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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Disrupting dehumanising and intersecting patterns of modernity with a relational ethic of caring

Publication Type: Academic Journal

Source(s): International Practice Development Journal, Vol 10, Iss 1, Pp 1-15 (2020)

Abstract: Background: This article describes two dehumanising patterns associated with modern culture and their consequences of stigma and suffering for persons living with dementia: the increasing division, judgment and exclusion of persons based on difference,...

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Engaging with Indigenous Australian communities for a human papilloma virus and oropharyngeal cancer project; use of the CONSIDER statement

Publication Type: Academic Journal

Source(s): BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-10 (2020)

Abstract: Abstract Background The prevalence of oral HPV infection and HPV-related oropharyngeal squamous cell carcinoma (OPSCC) among Indigenous Australians is unknown. This paper outlines the engagement, consultation and recruitment strategies for a study invo...

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