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Modern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution

Publication Type: Academic Journal

Source(s): Radiation Oncology, Vol 15, Iss 1, Pp 1-9 (2020)

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Abstract: Abstract Background Transoral surgery (TOS), particularly transoral robotic surgery (TORS) has become the preferred modality in the United States for the treatment of early stage oropharyngeal cancer, largely due to assumptions of fewer toxicities and ...

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Does HPV Subtype Predict Outcomes in Head and Neck Cancers?

Publication Type: Academic Journal

Source(s): International Journal of Otolaryngology, Vol 2021 (2021)

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Abstract: Background. Recently, reanalysis of The Cancer Genome Atlas study demonstrated that human papillomavirus (HPV) genotypes in head and neck cancers other than HPV-16 have inferior survival to HPV-16-positive tumors. We aimed to examine the association of...

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Assessing the Completeness of Reporting in Preclinical Oncolytic Virus Therapy Studies

Publication Type: Academic Journal

Source(s): Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 179-187 (2019)

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Abstract: Irreproducibility of preclinical findings could be a significant barrier to the “bench-to-bedside” development of oncolytic viruses (OVs). A contributing factor is the incomplete and non-transparent reporting of study methodology and design. Using the ...

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Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 15, Iss 9, p e0239315 (2020)

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Abstract: Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that is typically resistant to chemotherapy and radiation. Alternative strategies to target this cancer at a molecular level are necessary in order to improve dismal outcomes...

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Analysis of the TCGA Dataset Reveals that Subsites of Laryngeal Squamous Cell Carcinoma Are Molecularly Distinct

Publication Type: Academic Journal

Source(s): Cancers, Vol 13, Iss 105, p 105 (2020)

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Abstract: Laryngeal squamous cell carcinoma (LSCC) from different subsites have distinct presentations and prognosis. In this study, we carried out a multiomic comparison of LSCC subsites. The Cancer Genome Atlas (TCGA) LSCC cohort was analyzed in the R statisti...

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Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 14, Iss 5, p e0215221 (2019)

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Abstract: Poor reporting quality may contribute to irreproducibility of results and failed 'bench-to-bedside' translation. Consequently, guidelines have been developed to improve the complete and transparent reporting of in vivo preclinical studies. To examine t...

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