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A metabarcode based (species) inventory of the northern Adriatic phytoplankton
Publication Type: Academic Journal
Source(s): Biodiversity Data Journal, Vol 11, Iss , Pp 1-50 (2023)
Abstract: The northern Adriatic is characterised as the coldest and most productive marine area of the Mediterranean, which is due to high nutrient levels introduced by river discharges, the largest of which is the Italian Po River (at the same time also the lar...
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract: Abstract The BCL-2 inhibitor Venetoclax is a promising agent for the treatment of acute myeloid leukemia (AML). However, many patients are refractory to Venetoclax, and resistance develops quickly. ATP-binding cassette (ABC) transporters mediate chemot...
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract: Abstract Pancreatic cancer (PC), one of the most aggressive and life-threatening human malignancies, is known for its resistance to cytotoxic therapies. This is increasingly ascribed to the subpopulation of undifferentiated cells, known as pancreatic c...
Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages
Publication Type: Academic Journal
Source(s): Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract: Abstract TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of brain tumors. However, due to the heterogeneity of cell populations that contribute to the TSPO-PET signal, imaging interpretation may be challenging. We...
A practical approach to genome assembly and annotation of Basidiomycota using the example of Armillaria
Publication Type: Academic Journal
Source(s): BioTechniques, Vol 75, Iss 3, Pp 115-128 (2023)
Abstract: Technological advancements in genome sequencing, assembly and annotation platforms and algorithms that resulted in several genomic studies have created an opportunity to further our understanding of the biology of phytopathogens, including Armillaria s...
Ictal and interictal SPECT with 99mTc‐HMPAO in presurgical epilepsy. I: Predictive value and methodological considerations
Publication Type: Academic Journal
Source(s): Epilepsia Open, Vol 8, Iss 3, Pp 1064-1074 (2023)
Abstract: Abstract Objective This retrospective study investigates the predictive value of ictal subtraction single‐photon emission computed tomography (SPECT) co‐registered to magnetic resonance imaging (MRI) (SISCOM) for successful epilepsy surgery. Methods 57...
Twenty‐five years of epilepsy surgery at a Central European comprehensive epilepsy center—Trends in intervention delay and outcomes
Publication Type: Academic Journal
Source(s): Epilepsia Open, Vol 8, Iss 3, Pp 991-1001 (2023)
Abstract: Abstract Objective We analyzed trends in patients' characteristics, outcomes, and waiting times over the last 25 years at our epilepsy surgery center situated in Central Europe to highlight possible areas of improvement in our care for patients with dr...
Misuse of tumor marker levels leads to an insufficient International Germ Cell Consensus Classification (IGCCCG) risk group assignment and impaired treatment
Publication Type: Academic Journal
Source(s): Cancer Medicine, Vol 12, Iss 16, Pp 16829-16836 (2023)
Abstract: Abstract Background Metastatic germ cell tumors of the testis (GCTs) are risk‐stratified according to the International Germ Cell Cancer Collaborative Group (IGCCCG) classification system. This risk classification is based on anatomical risk factors as...
Combining nitric oxide and calcium sensing for the detection of endothelial dysfunction
Publication Type: Academic Journal
Source(s): Communications Chemistry, Vol 6, Iss 1, Pp 1-22 (2023)
Abstract: Abstract Cardiovascular diseases are the leading cause of death worldwide and are not typically diagnosed until the disease has manifested. Endothelial dysfunction is an early, reversible precursor in the irreversible development of cardiovascular dise...
Extracting Insights From Competitor's Mistakes: A Sentiment Analysis Approach Using Competitive set Online Reviews
Publication Type: Academic Journal
Source(s): TEM Journal, Vol 12, Iss 3, Pp 1754-1761 (2023)
Abstract: Sentiment analysis was used to understand the key aspects of the hotel quest stay with emphasis on the drivers of positive/negative experience. Other studies evaluated the impact of the online reputation on the business performance but the minority of ...