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Advanced Search Results For "Mathis, William"

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 "Mathis, William"
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ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

Publication Type: Academic Journal

Source(s): Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)

Abstract: The role of ADAMTSL3 in heart pathology and cardiac disease is investigated with Adamtsl3-deficient mice using CRISPR-Cas9 gene editing.

Late dominance of the right hemisphere during narrative comprehension

Publication Type: Academic Journal

Source(s): NeuroImage, Vol 264, Iss , Pp 119749- (2022)

Abstract: PET and fMRI studies suggest that auditory narrative comprehension is supported by a bilateral multilobar cortical network. The superior temporal resolution of magnetoencephalography (MEG) makes it an attractive tool to investigate the dynamics of how ...

Prediction of postoperative cardiac events in multiple surgical cohorts using a multimodal and integrative decision support system

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Postoperative patients are at risk of life-threatening complications such as hemodynamic decompensation or arrhythmia. Automated detection of patients with such risks via a real-time clinical decision support system may provide opportunities f...


Population pharmacokinetic modeling and simulations of berotralstat for prophylactic treatment of attacks of hereditary angioedema

Publication Type: Academic Journal

Source(s): Clinical and Translational Science, Vol 15, Iss 4, Pp 1027-1035 (2022)

Abstract: Abstract Hereditary angioedema (HAE) is an autosomal dominant disorder characterized by recurrent episodes of swelling of the skin, larynx, gastrointestinal tract, genitals, and extremities that can be disruptive to patient quality of life. Dysregulati...

Automating Pitted Red Blood Cell Counts Using Deep Neural Network Analysis: A New Method for Measuring Splenic Function in Sickle Cell Anaemia

Publication Type: Academic Journal

Source(s): Frontiers in Physiology, Vol 13 (2022)

Abstract: The spleen plays an important role in the body’s defence against bacterial infections. Measuring splenic function is of interest in multiple conditions, including sickle cell anaemia (SCA), where spleen injury occurs early in life. Unfortunately, there...

Sex Modulates the Pathological Aging Effect on Caudate Functional Connectivity in Mild Cognitive Impairment

Publication Type: Academic Journal

Source(s): Frontiers in Psychiatry, Vol 13 (2022)

Abstract: PurposeTo assess the pathological aging effect on caudate functional connectivity among mild cognitive impairment (MCI) participants and examine whether and how sex and amyloid contribute to this process.Materials and MethodsTwo hundred and seventy-sev...

(Re-)Negotiating Ambiguity’s (Added) Value(lessness)

Publication Type: Academic Journal

Source(s): On_Culture, Vol 12 (2021)

Abstract: What would an issue on ambiguity be without countering the affirmative calls for a concept that established itself as an aesthetic paradigm and thus as a norm in art discourse as early as around 1800? To answer this, this multi-voiced _Perspective is d...

Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse

Publication Type: Academic Journal

Source(s): Frontiers in Physiology, Vol 12 (2021)

Abstract: Dysfunctional sarcoplasmic reticulum Ca2+ handling is commonly observed in heart failure, and thought to contribute to arrhythmogenesis through several mechanisms. Some time ago we developed a cardiomyocyte-specific inducible SERCA2 knockout mouse, whi...

Systemic Administration of α7-Nicotinic Acetylcholine Receptor Ligands Does Not Improve Renal Injury or Behavior in Mice With Advanced Systemic Lupus Erythematosus

Publication Type: Academic Journal

Source(s): Frontiers in Medicine, Vol 8 (2021)

Abstract: There is a critical need for safe treatment options to control inflammation in patients with systemic lupus erythematosus (SLE) since the inflammation contributes to morbidity and mortality in advanced disease. Endogenous neuroimmune mechanisms like th...