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Estimating incidence of type 1 and type 2 diabetes using prevalence data: the SEARCH for Diabetes in Youth study
Publication Type: Academic Journal
Source(s): BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract: Abstract Background Incidence is one of the most important epidemiologic indices in surveillance. However, determining incidence is complex and requires time-consuming cohort studies or registries with date of diagnosis. Estimating incidence from preva...
Machine learning classification of chronic traumatic brain injury using diffusion tensor imaging and NODDI: A replication and extension study
Publication Type: Academic Journal
Source(s): Neuroimage: Reports, Vol 3, Iss 1, Pp 100157- (2023)
Abstract: Individuals with acute and chronic traumatic brain injury (TBI) are associated with unique white matter (WM) structural abnormalities, including fractional anisotropy (FA) differences. Our research group previously used FA as a feature in a linear supp...
A progeroid syndrome caused by a deep intronic variant in TAPT1 is revealed by RNA/SI‐NET sequencing
Publication Type: Academic Journal
Source(s): EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract: Abstract Exome sequencing has introduced a paradigm shift for the identification of germline variations responsible for Mendelian diseases. However, non‐coding regions, which make up 98% of the genome, cannot be captured. The lack of functional annotat...
Obesity is associated with a distinct brain-gut microbiome signature that connects Prevotella and Bacteroides to the brain’s reward center
Publication Type: Academic Journal
Source(s): Gut Microbes, Vol 14, Iss 1 (2022)
Abstract: The prevalence of obesity has risen to its highest values over the last two decades. While many studies have either shown brain or microbiome connections to obesity, few have attempted to analyze the brain-gut-microbiome relationship in a large cohort ...
Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF
Publication Type: Academic Journal
Source(s): Open Heart, Vol 9, Iss 2 (2022)
Abstract: Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. We examine the influence of BMI on outcomes and whether this is modi...
Epidemiology of Treated Diabetes Ocular Complications in France 2008–2018—The LANDSCAPE French Nationwide Study
Publication Type: Academic Journal
Source(s): Pharmaceutics, Vol 14, Iss 2330, p 2330 (2022)
Abstract: Aim: LANDSCAPE aimed to estimate the annual incidence and prevalence of treated diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) between 2008 and 2018. Methods: This French nationwide observational study used data from the Fren...
Incidence and Prevalence of Neovascular Age-Related Macular Degeneration in France between 2008 and 2018
Publication Type: Academic Journal
Source(s): Ophthalmology Science, Vol 2, Iss 1, Pp 100114- (2022)
Abstract: Purpose: This study aimed to estimate the incidence and prevalence of neovascular age-related macular degeneration (nAMD) in the French population between 2008 and 2018. Design: This was a retrospective, longitudinal population study using health care ...
Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis
Publication Type: Academic Journal
Source(s): JCI Insight, Vol 7, Iss 4 (2022)
Abstract: Mitophagy and mitochondrial integrated stress response (ISR) are 2 primary protective mechanisms to maintain functional mitochondria. Whether these 2 processes are coordinately regulated remains unclear. Here we show that mitochondrial fission 1 protei...
Trends in Glycemia between 2002 and 2016 among Incident Youth Cohorts Early in the Course of Type 1 Diabetes: The SEARCH for Diabetes in Youth Study
Publication Type: Academic Journal
Source(s): Journal of Diabetes Research, Vol 2022 (2022)
Abstract: Objective. Hyperglycemia early in the course of type 1 diabetes (T1D) may increase the risk of cardiometabolic complications later in life. We tested the hypothesis that there were temporal trends in population-level glycemia and insulin pump use near ...
Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry
Publication Type: Academic Journal
Source(s): Hellenic Journal of Cardiology, Vol 62, Iss 2, Pp 152-157 (2021)
Abstract: Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific ...