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Advanced Search Results For "McDowell, Daniel"

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 "McDowell, Daniel"
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Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer

Publication Type: Academic Journal

Source(s): Emerging Microbes and Infections, Vol 11, Iss 1, Pp 95-112 (2022)

Abstract: SARS-CoV-2 was first reported circulating in human populations in December 2019 and has since become a global pandemic. Recent history involving SARS-like coronavirus outbreaks have demonstrated the significant role of intermediate hosts in viral maint...

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Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant

Publication Type: Academic Journal

Source(s): Emerging Microbes and Infections, Vol 11, Iss 1, Pp 662-675 (2022)

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for a global pandemic that has had significant impacts on human health and economies worldwide. SARS-CoV-2 is highly transmissible and the cause of coronavirus disease 2019 in ...

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Diversity and Rabbinization : Jewish Texts and Societies Between 400 and 1000 CE

Diversity and Rabbinization : Jewish Texts and Societies Between 400 and 1000 CE

Publication Type: eBook

Abstract: This volume is dedicated to the cultural and religious diversity in Jewish communities from Late Antiquity to the Early Middle Age and the growing influence of the rabbis within these communities during the same period. Drawing on available textual and...

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Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Abstract: Here, Rathnasinghe et al. characterize the pathogenesis of a mouse-adapted SARS-CoV-2 in infected obese and aged mice, and identify mutations that are present in SARS-CoV-2 variants of concern, associated with higher transmissibility.

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Refractive Growth of the Crystalline Lens in the Infant Aphakia Treatment Study

Publication Type: Academic Journal

Source(s): Ophthalmology Science, Vol 2, Iss 4, Pp 100208- (2022)

Abstract: Objective: To compare the rate of refractive growth (RRG3) of the crystalline lens (“lens”) versus the eye excluding the lens (“globe”) for the fellow, noncataractous eyes of participants in the Infant Aphakia Treatment Study. Design: Retrospective coh...

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Multi-scale quantification of anthropogenic, fire, and drought-associated forest disturbances across the continental U.S., 2000–2014

Publication Type: Academic Journal

Source(s): Frontiers in Forests and Global Change, Vol 5 (2022)

Abstract: Our understanding of broad-scale forest disturbances under climatic extremes remains incomplete. Drought, as a typical extreme event, is a key driver of forest mortality but there have been no reports on continental-scale quantification of its impact o...

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Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a randomised, triple-blind, allocation concealed, placebo-controlled phase 2 trial

Publication Type: Academic Journal

Source(s): Trials, Vol 23, Iss 1, Pp 1-15 (2022)

Abstract: Abstract Background Mesenchymal stromal cells (MSCs) may be of benefit in ARDS due to immunomodulatory and reparative properties. This trial investigates a novel CD362 enriched umbilical cord derived MSC product (REALIST ORBCEL-C), produced to Good Man...

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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborative for Audit and Research (NITCAR)

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 12, Iss 7 (2022)

Abstract: Objectives To assess practice in the care of adults with suspected community-acquired bacterial meningitis in the UK and Ireland.Design Retrospective cohort study.Setting 64 UK and Irish hospitals.Participants 1471 adults with community-acquired mening...

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Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT

Publication Type: Academic Journal

Source(s): Health Technology Assessment, Vol 26, Iss 18 (2022)

Abstract: Background: Daily assessment of patient readiness for liberation from invasive mechanical ventilation can reduce the duration of ventilation. However, there is uncertainty about the effectiveness of this in a paediatric population. Objectives: To deter...

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Bidirectional Associations Between Depressive and Anxiety Symptoms and Loneliness During the COVID-19 Pandemic: Dynamic Panel Models With Fixed Effects

Publication Type: Academic Journal

Source(s): Frontiers in Psychiatry, Vol 12 (2021)

Abstract: Background: Understanding the direction and magnitude of mental health-loneliness associations across time is important to understand how best to prevent and treat mental health and loneliness. This study used weekly data collected over 8 weeks through...

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