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PrImary decompressive Craniectomy in AneurySmal Subarachnoid hemOrrhage (PICASSO) trial: study protocol for a randomized controlled trial
Publication Type: Academic Journal
Source(s): Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract: Abstract Background Poor-grade aneurysmal subarachnoid hemorrhage (SAH) is associated with poor neurological outcome and high mortality. A major factor influencing morbidity and mortality is brain swelling in the acute phase. Decompressive craniectomy ...
Machine learning and ontology in eCoaching for personalized activity level monitoring and recommendation generation
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-26 (2022)
Abstract: Abstract Leading a sedentary lifestyle may cause numerous health problems. Therefore, passive lifestyle changes should be given priority to avoid severe long-term damage. Automatic health coaching system may help people manage a healthy lifestyle with ...
Vernakuläre Wissenschaftskommunikation : Beiträge zur Entstehung und Frühgeschichte der modernen deutschen Wissenschaftssprachen
Publication Type: eBook
Abstract: Der sich vom 16. bis zum 19. Jahrhundert vollziehende Übergang der weitgehend lateinbasierten europäischen Gelehrtenkultur zu einem vernakulär-mehrsprachigen „modernen“ Wissenschaftssystem ist bislang für den deutschen Sprachraum nur bruchstückhaft bes...
PD-1/CTLA-4 blockade leads to expansion of CD8+PD-1int TILs and results in tumor remission in experimental liver cancer
Publication Type: Academic Journal
Source(s): Liver Cancer (2022)
Abstract: Background: Checkpoint inhibitors act on exhausted CD8+ T cells and restore their effector function in chronic infections and cancer. The underlying mechanisms of action appear to differ between different types of cancer and are not yet fully understoo...
Coherent response of the electronic system driven by non-interfering laser pulses
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Abstract: Light–matter interaction is expected to be isotropic in free-electron-like materials. Here, by using time- and phase-resolved photoemission, the authors observe signatures of an anisotropic interaction on a noble metal surface, that can only be account...
Barriers to Optimal Child Sleep among Families with Low Income: A Mixed-Methods Study to Inform Intervention Development
Publication Type: Academic Journal
Source(s): International Journal of Environmental Research and Public Health, Vol 20, Iss 862, p 862 (2023)
Abstract: This study gathered formative data on barriers to optimal child sleep to inform the development of a sleep intervention for parents of preschool-aged children in low-income households. Parents (n = 15, age: 34 ± 8 years, household income: $30,000 ± 17,...
The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis
Publication Type: Academic Journal
Source(s): Hepatology Communications, Vol 6, Iss 2, Pp 320-333 (2022)
Abstract: Nonalcoholic steatohepatitis (NASH) is induced by steatosis and metabolic inflammation. While involvement of the innate immune response has been shown, the role of the adaptive immune response in NASH remains controversial. Likewise, the role of regula...
Soluble suppression of tumorigenicity 2 as outcome predictor after cardiopulmonary resuscitation: an observational prospective study
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract: Abstract Prognostication after cardiopulmonary resuscitation (CPR) is complex. Novel biomarkers like soluble suppression of tumorigenicity 2 (sST2) may provide an objective approach. A total of 106 post-CPR patients were included in this single-center ...
Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences, Vol 23, Iss 10914, p 10914 (2022)
Abstract: Donor lymphocyte infusion (DLI) can (re-)induce durable remission in relapsing patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT). However, DLI harbors the risk of increased non-relapse mortality due to the co-occurrence of gr...