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Advanced Search Results For "Middleton, Anne"

1 - 10 of 562 results for
 "Middleton, Anne"
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Treatment fidelity monitoring, reporting and findings in a complex aphasia intervention trial: a substudy of the Very Early Rehabilitation in SpEech (VERSE) trial

Publication Type: Academic Journal

Source(s): Trials, Vol 23, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background Treatment fidelity is inconsistently reported in aphasia research, contributing to uncertainty about the effectiveness of types of aphasia therapy following stroke. We outline the processes and outcomes of treatment fidelity monitor...

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Gut microbiota predicts body fat change following a low-energy diet: a PREVIEW intervention study

Publication Type: Academic Journal

Source(s): Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)

Abstract: Abstract Background Low-energy diets (LEDs) comprise commercially formulated food products that provide between 800 and 1200 kcal/day (3.3–5 MJ/day) to aid body weight loss. Recent small-scale studies suggest that LEDs are associated with marked change...

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How Can the EU Beating Cancer Plan Help in Tackling Lung Cancer, Colorectal Cancer, Breast Cancer and Melanoma?

Publication Type: Academic Journal

Source(s): Healthcare, Vol 10, Iss 1618, p 1618 (2022)

Abstract: Cancer is the second leading cause of mortality in EU countries, and the needs to tackle cancer are obvious. New scientific understanding, techniques and methodologies are opening up horizons for significant improvements in diagnosis and care. However,...

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Remarkable Resilience of Forest Structure and Biodiversity Following Fire in the Peri-Urban Bushland of Sydney, Australia

Publication Type: Academic Journal

Source(s): Climate, Vol 10, Iss 86, p 86 (2022)

Abstract: In rapidly urbanizing areas, natural vegetation becomes fragmented, making conservation planning challenging, particularly as climate change accelerates fire risk. We studied urban forest fragments in two threatened eucalypt-dominated (scribbly gum woo...

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Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract: Abstract Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk. This study aimed to assess syndecan-1 as a biomarker for small...

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Impacts of detritivore diversity loss on instream decomposition are greatest in the tropics

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Abstract: It is unclear whether stream detritivore diversity enhances decomposition across climates. Here the authors manipulate litter diversity and examine detritivore assemblages in a globally distributed stream litterbag experiment, finding a positive divers...

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Anti-CD37 radioimmunotherapy with 177Lu-NNV003 synergizes with the PARP inhibitor olaparib in treatment of non-Hodgkin's lymphoma in vitro.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 17, Iss 4, p e0267543 (2022)

Abstract: Background and purposePARP inhibitors have been shown to increase the efficacy of radiotherapy in preclinical models. Radioimmunotherapy results in selective radiation cytotoxicity of targeted tumour cells. Here we investigate the combined effect of an...

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Demonstrating trustworthiness when collecting and sharing genomic data: public views across 22 countries

Publication Type: Academic Journal

Source(s): Genome Medicine, Vol 13, Iss 1, Pp 1-12 (2021)

Abstract: Abstract Background Public trust is central to the collection of genomic and health data and the sustainability of genomic research. To merit trust, those involved in collecting and sharing data need to demonstrate they are trustworthy. However, it is ...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type: Academic Journal

Source(s): iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract: Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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A Structural Model for the Ligand Binding of Pneumococcal Serotype 3 Capsular Polysaccharide-Specific Protective Antibodies

Publication Type: Academic Journal

Source(s): mBio, Vol 12, Iss 3 (2021)

Abstract: Infectious diseases caused by pathogenic bacteria are a major threat to human health. Capsular polysaccharides (CPSs) of many pathogenic bacteria have been used as the main components of glycoconjugate vaccines against bacterial diseases in clinical pr...

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