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Advanced Search Results For "Moses, Lucia"

1 - 10 of 4,755 results for
 "Moses, Lucia"
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Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

Publication Type:Academic Journal

Source(s):The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)

Abstract:Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type:Academic Journal

Source(s):iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract:Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial

Publication Type:Academic Journal

Source(s):The Lancet Global Health, Vol 7, Iss 1, Pp e132-e147 (2019)

Abstract:Summary: Background: Child stunting reduces survival and impairs neurodevelopment. We tested the independent and combined effects of improved water, sanitation, and hygiene (WASH), and improved infant and young child feeding (IYCF) on stunting and anae...

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Quantile Mapping Bias Correction on Rossby Centre Regional Climate Models for Precipitation Analysis over Kenya, East Africa

Publication Type:Academic Journal

Source(s):Water, Vol 12, Iss 3, p 801 (2020)

Abstract:This study uses the quantile mapping bias correction (QMBC) method to correct the bias in five regional climate models (RCMs) from the latest output of the Rossby Center Climate Regional Model (RCA4) over Kenya. The outputs were validated using various...

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Evaluation of Meteorological Drought and Flood Scenarios over Kenya, East Africa

Publication Type:Academic Journal

Source(s):Atmosphere, Vol 11, Iss 3, p 307 (2020)

Abstract:This work examines drought and flood events over Kenya from 1981 to 2016 using the Standardized Precipitation−Evapotranspiration Index (SPEI). The spatiotemporal analysis of dry and wet events was conducted for 3 and 12 months. Extreme drought incidenc...

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Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 213-226.e3 (2018)

Abstract:Summary: Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer types from The Cance...

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Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 297-312.e12 (2018)

Abstract:Summary: Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer pathways, oncogenes, and tumor suppressors (cancer genes) b...

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Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 194-212.e6 (2018)

Abstract:Summary: This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smoking and/or human papillomavirus (HPV). SCCs harbor 3q, 5p, a...

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The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 313-326.e5 (2018)

Abstract:Summary: Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic sub...

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Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 227-238.e3 (2018)

Abstract:Summary: Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools. We identified a total of 25,664 fusions, with a 63% ...

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