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Contextualising the association of socioeconomic deprivation with hospitalisation rates of myocardial infarction in a rural area in eastern Germany
Publication Type: Academic Journal
Source(s): Rural and Remote Health, Vol 22 (2022)
Abstract: Introduction: Evidence on the association of socioeconomic deprivation with occurrence of acute myocardial infarction (AMI) is available from international studies and urban settings in western Germany. This study aimed to assess this association based...
Educating Pharmacists on the Risks of Strong Opioids With Descriptive and Simulated Experience Risk Formats: A Randomized Controlled Trial
Publication Type: Academic Journal
Source(s): MDM Policy & Practice, Vol 6 (2021)
Abstract: Objectives. High opioid prescription rates in the United States and Europe suggest miscalibrated risk perceptions among those who prescribe, dispense, and take opioids. Findings from cognitive decision science suggest that risk perceptions and behavior...
Safety and clinical impact of FEES – results of the FEES-registry
Publication Type: Academic Journal
Source(s): Neurological Research and Practice, Vol 1, Iss 1, Pp 1-8 (2019)
Abstract: Abstract Background At present, the flexible endoscopic evaluation of swallowing (FEES) is one of the most commonly used methods for the objective assessment of swallowing. This multicenter trial prospectively collected data on the safety of FEES and a...
A systematic literature review of evidence-based clinical practice for rare diseases: what are the perceived and real barriers for improving the evidence and how can they be overcome?
Publication Type: Academic Journal
Source(s): Trials, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract: Abstract Background Evidence-based clinical practice is challenging in all fields, but poses special barriers in the field of rare diseases. The present paper summarises the main barriers faced by clinical research in rare diseases, and highlights oppo...
BDNF Serum Levels are Associated With White Matter Microstructure in Schizophrenia - A Pilot Study
Publication Type: Academic Journal
Source(s): Frontiers in Psychiatry, Vol 11 (2020)
Abstract: Brain derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of schizophrenia. As BDNF regulates axonal and dendritic growth, altered BDNF levels in schizophrenia patients might underlie changes in structural connectivity that ha...
Corrigendum: Nerve Growth Factor Serum Levels Are Associated With Regional Gray Matter Volume Differences in Schizophrenia Patients
Publication Type: Academic Journal
Source(s): Frontiers in Psychiatry, Vol 10 (2019)
Nerve Growth Factor Serum Levels Are Associated With Regional Gray Matter Volume Differences in Schizophrenia Patients
Publication Type: Academic Journal
Source(s): Frontiers in Psychiatry, Vol 10 (2019)
Abstract: Numerous neuroimaging studies have revealed structural brain abnormalities in schizophrenia patients. There is emerging evidence that dysfunctional nerve growth factor (NGF) signaling may contribute to structural brain alterations found in these patien...
Evidence-based practice within nutrition: what are the barriers for improving the evidence and how can they be dealt with?
Publication Type: Academic Journal
Source(s): Trials, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract: Abstract Background Evidence-based clinical research poses special barriers in the field of nutrition. The present review summarises the main barriers to research in the field of nutrition that are not common to all randomised clinical trials or trials...
Specific barriers to the conduct of randomised clinical trials on medical devices
Publication Type: Academic Journal
Source(s): Trials, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract: Abstract Background Medical devices play an important role in the diagnosis, prevention, treatment and care of diseases. However, compared to pharmaceuticals, there is no rigorous formal regulation for demonstration of benefits and exclusion of harms t...
Barriers to the conduct of randomised clinical trials within all disease areas
Publication Type: Academic Journal
Source(s): Trials, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract: Abstract Background Randomised clinical trials are key to advancing medical knowledge and to enhancing patient care, but major barriers to their conduct exist. The present paper presents some of these barriers. Methods We performed systematic literatur...