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Advanced Search Results For "Nick Daneman"

1 - 10 of 613 results for
 "Nick Daneman"
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Antimicrobial resistance and mortality following E. coli bacteremiaResearch in context

Publication Type: Academic Journal

Source(s): EClinicalMedicine, Vol 56, Iss , Pp 101781- (2023)

Abstract: Summary: Background: Global estimates suggest millions of deaths annually are associated with antimicrobial resistance (AMR) but these are generated from scarce data on the relative risk of death attributable to drug-resistant versus drug-sensitive inf...

Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity

Publication Type: Academic Journal

Source(s): BMJ Paediatrics Open, Vol 6, Iss 1 (2022)

Abstract: Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify...

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Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study

Publication Type: Academic Journal

Source(s): BMC Pediatrics, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background Bloodstream infections (BSIs) cause significant morbidity and mortality in critically ill children but treatment duration is understudied. We describe the durations of antimicrobial treatment that critically ill children receive and...

Regional variation in the potentially inappropriate first-line use of fluoroquinolones in Canada as a key to antibiotic stewardship? A drug utilization review study

Publication Type: Academic Journal

Source(s): BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)

Abstract: Abstract Background Serious adverse effects of fluoroquinolone antibiotics have been described for more than decade. Recently, several drug regulatory agencies have advised restricting their use in milder infections for which other treatments are avail...

Initial antimicrobial management of sepsis

Publication Type: Academic Journal

Source(s): Critical Care, Vol 25, Iss 1, Pp 1-11 (2021)

Abstract: Abstract Sepsis is a common consequence of infection, associated with a mortality rate > 25%. Although community-acquired sepsis is more common, hospital-acquired infection is more lethal. The most common site of infection is the lung, followed by abdo...

A Time Series Analysis Evaluating Antibiotic Prescription Rates in Long-Term Care during the COVID-19 Pandemic in Alberta and Ontario, Canada

Publication Type: Academic Journal

Source(s): Antibiotics, Vol 11, Iss 1001, p 1001 (2022)

Abstract: The COVID-19 pandemic affected access to care, and the associated public health measures influenced the transmission of other infectious diseases. The pandemic has dramatically changed antibiotic prescribing in the community. We aimed to determine the ...

Antibiotic treatment duration for bloodstream infections in critically ill children-A survey of pediatric infectious diseases and critical care clinicians for clinical equipoise.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 17, Iss 7, p e0272021 (2022)

Abstract: ObjectiveTo describe antibiotic treatment durations that pediatric infectious diseases (ID) and critical care clinicians usually recommend for bloodstream infections in critically ill children.DesignAnonymous, online practice survey using five common p...

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Neighbourhood-level socio-demographic characteristics and risk of COVID-19 incidence and mortality in Ontario, Canada: A population-based study

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 17, Iss 10 (2022)

Abstract: Objectives We aimed to estimate associations between COVID-19 incidence and mortality with neighbourhood-level immigration, race, housing, and socio-economic characteristics. Methods We conducted a population-based study of 28,808 COVID-19 cases in the...

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Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial

Publication Type: Academic Journal

Source(s): Trials, Vol 22, Iss 1, Pp 1-17 (2021)

Abstract: Abstract Background Convalescent plasma has been used for numerous viral diseases including influenza, severe acute respiratory syndrome, Middle East respiratory syndrome and Ebola virus; however, evidence to support its use is weak. SARS-CoV-2 is a no...

Post-exposure prophylaxis against SARS-CoV-2 in close contacts of confirmed COVID-19 cases (CORIPREV): study protocol for a cluster-randomized trial

Publication Type: Academic Journal

Source(s): Trials, Vol 22, Iss 1, Pp 1-16 (2021)

Abstract: Abstract Background Post-exposure prophylaxis (PEP) is a well-established strategy for the prevention of infectious diseases, in which recently exposed people take a short course of medication to prevent infection. The primary objective of the COVID-19...

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