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Advanced Search Results For "Niknafs N"

1 - 10 of 95 results for
 "Niknafs N"
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Genomic characterization of malignant progression in neoplastic pancreatic cysts

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Abstract: Neoplastic pancreatic cysts are associated with invasive pancreatic cancer, but their origins and evolutionary relationships are unclear. Here, the authors present the evolutionary analysis of neoplastic cysts and report them as precursors of invasive ...


Applying accreditation standards in a self-evaluation process: The experience of Educational Development Center of Tehran University of Medical Sciences

Publication Type: Academic Journal

Source(s): Journal of Medical Education and Development, Vol 10, Iss 4, Pp 340-351 (2016)

Abstract: Introduction: Educational Development Centers (EDCs), as the coordinator in education development in Medical Sciences universities, in order to improve their quality should evaluate their activities. In spite of remarkable performance of Tehran Univers...

A probabilistic model to predict clinical phenotypic traits from genome sequencing.

Publication Type: Academic Journal

Source(s): PLoS Computational Biology, Vol 10, Iss 9, p e1003825 (2014)

Abstract: Genetic screening is becoming possible on an unprecedented scale. However, its utility remains controversial. Although most variant genotypes cannot be easily interpreted, many individuals nevertheless attempt to interpret their genetic information. In...

OA12.01 Genomic and Immune Cell Landscape of Response to Chemo-Immunotherapy in Malignant Pleural Mesothelioma.

Publication Type: Academic Journal

Source(s): Journal of Thoracic Oncology; 2021 Supplement, Vol. 16 Issue 10, pS867-S868, 2p

Genome-wide cell-free DNA fragmentation in patients with cancer.

Publication Type: Academic Journal

Source(s): Nature; 6/20/2019, Vol. 570 Issue 7761, p385-389, 5p, 1 Diagram, 2 Charts, 12 Graphs

Abstract: Copyright of Nature is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articl...

Persistent mutation burden drives sustained anti-tumor immune responses

Publication Type: Periodical

Source(s): Nature Medicine; 20230101, Issue: Preprints p1-10, 10p

Abstract: Tumor mutation burden is an imperfect proxy of tumor foreignness and has therefore failed to consistently demonstrate clinical utility in predicting responses in the context of immunotherapy. We evaluated mutations in regions of the genome that are unl...

Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial

Publication Type: Periodical

Source(s): Nature Medicine; November 2021, Vol. 27 Issue: 11 p1910-1920, 11p

Abstract: Mesothelioma is a rare and fatal cancer with limited therapeutic options until the recent approval of combination immune checkpoint blockade. Here we report the results of the phase 2 PrE0505 trial (NCT02899195) of the anti-PD-L1 antibody durvalumab pl...

HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade.

Publication Type: Academic Journal

Source(s): Annals of Oncology. Jul2022, Vol. 33 Issue 7, p728-738. 11p.

Abstract: Whereas human leukocyte antigen (HLA) class I mutation-associated neoantigen burden has been linked with response to immune checkpoint blockade (ICB), the role of HLA class II-restricted neoantigens in clinical responses to ICB is less studied. We used...