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Advanced Search Results For "North, James"

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 "North, James"
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Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

Abstract: Bacteria and archaea use tripartite ATP-independent periplasmic (TRAP) transporters to import essential nutrients. Davies et al. report a high resolution structure of a TRAP and show that it uses an ‘elevator-with-an operator’ mechanism.


Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Publication Type: Academic Journal

Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)

Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...

iWetland: A Community Science Platform for Monitoring Wetland Water Levels

Publication Type: Academic Journal

Source(s): Citizen Science: Theory and Practice, Vol 8, Iss 1 (2023)

Abstract: iWetland is a community science wetland water level monitoring platform developed by the McMaster Ecohydrology Lab and tested from 2016 to 2019 in wetlands located east of Georgian Bay, Ontario, Canada. The goal of iWetland is to engage community membe...

Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 12, Iss 11 (2022)

Abstract: Objectives Hospital-acquired pressure injuries (PIs) are a source of morbidity and mortality, and many are potentially preventable.Design This study prospectively evaluated the prevalence and the associated factors of PIs in adult critical care patient...


The North American tree‐ring fire‐scar network

Publication Type: Academic Journal

Source(s): Ecosphere, Vol 13, Iss 7, Pp n/a-n/a (2022)

Abstract: Abstract Fire regimes in North American forests are diverse and modern fire records are often too short to capture important patterns, trends, feedbacks, and drivers of variability. Tree‐ring fire scars provide valuable perspectives on fire regimes, in...

AusTraits, a curated plant trait database for the Australian flora

Publication Type: Academic Journal

Source(s): Scientific Data, Vol 8, Iss 1, Pp 1-20 (2021)

Abstract: Measurement(s) plant trait Technology Type(s) digital curation Sample Characteristic - Organism Viridiplantae Sample Characteristic - Location Australia Machine-accessible metadata file describing the reported data:


Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections

Publication Type: Academic Journal

Source(s): JCI Insight, Vol 7, Iss 2 (2022)

Abstract: Isolation guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are largely derived from data collected prior to the emergence of the delta variant. We followed a cohort of ambulatory patients with postvaccination breakthrough SAR...

Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

Publication Type: Academic Journal

Source(s): Cell Genomics, Vol 2, Iss 1, Pp 100084- (2022)

Abstract: Summary: Genetic studies on telomere length are important for understanding age-related diseases. Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based association study for TL acro...

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Abstract: The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq...


Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

Publication Type: Academic Journal

Source(s): Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)

Abstract: Abstract Background Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered breathing remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) p...