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Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institute of Emory University Experience
Publication Type: Academic Journal
Source(s): Journal of Immunotherapy and Precision Oncology, Pp 52-57 (2022)
Abstract: Introduction: There are three combination immune checkpoint inhibitor (ICI)–based regimens in the first-line setting for metastatic renal cell carcinoma (mRCC). Currently, there is limited real-world data for clinical outcomes and toxicity in mRCC pati...
Strategies for recruiting, training, and retaining educators for adolescent pregnancy prevention programs: Insights from organization leaders and educators
Publication Type: Academic Journal
Source(s): Dialogues in Health, Vol 1, Iss , Pp 100052- (2022)
Abstract: This paper provides insights into how 17 community-based organizations (CBOs) recruited, trained, and retained educators in pregnancy prevention program implementations for underserved adolescents in different areas of the United States. The paper also...
New or enlarging hiatal hernias after thoracic surgery for early lung cancerCentral MessagePerspective
Publication Type: Academic Journal
Source(s): JTCVS Open, Vol 10, Iss , Pp 415-423 (2022)
Abstract: Objective: The study objective was to determine the relationship between lung resection and the development of postoperative hiatal hernia. Methods: Preoperative and postoperative computed tomography imaging from 373 patients from the International Ear...
Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic
Publication Type: Academic Journal
Source(s): Critical Care Explorations, Vol 4, Iss 4, p e0686 (2022)
Abstract: OBJECTIVES:. To describe the prevalence, associated risk factors, and outcomes of serious neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) among patients hospitalized with severe acute respiratory syndrome corona...
Busulfan Treatment for Myeloproliferative Disease may Reduce Injection Burden in Vascular Endothelial Growth Factor-Driven Retinopathy
Publication Type: Academic Journal
Source(s): American Journal of Ophthalmology Case Reports, Vol 26, Iss , Pp 101554- (2022)
Abstract: Purpose: Myeloproliferative neoplasms (MPNs) have been associated with increased systemic levels of vascular endothelial growth factor (VEGF). This study investigated an association between systemic busulfan for treatment of MPN and the requirement for...
Defining Terms Used for Animals Working in Support Roles for People with Support Needs
Publication Type: Academic Journal
Source(s): Animals, Vol 12, Iss 1975, p 1975 (2022)
Abstract: The nomenclature used to describe animals working in roles supporting people can be confusing. The same term may be used to describe different roles, or two terms may mean the same thing. This confusion is evident among researchers, practitioners, and ...
Cryptococcus gattii endogenous chorioretinitis
Publication Type: Academic Journal
Source(s): American Journal of Ophthalmology Case Reports, Vol 25, Iss , Pp 101283- (2022)
Abstract: Purpose: To present a case of subretinal abscess associated with pneumonia and meningitis caused by Cryptococcus gattii in an immunocompetent host. Observations: A 37-year-old man presented with sub-acute painless unilateral vision loss and a white sub...
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract: Arginine methylation has been reported to regulate AKT-associated signalling. Here, the authors show that PRMT5-mediated arginine methylation promotes AKT activity and induces tumourigenesis.
Ecosystem response persists after a prolonged marine heatwave
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract: Abstract Some of the longest and most comprehensive marine ecosystem monitoring programs were established in the Gulf of Alaska following the environmental disaster of the Exxon Valdez oil spill over 30 years ago. These monitoring programs have been su...
Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
Publication Type: Academic Journal
Source(s): Critical Care Explorations, Vol 3, Iss 8, p e0514 (2021)
Abstract: IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology ...