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A Hybrid Likelihood Model for Sequence-Based Disease Association Studies.

Publication Type: Academic Journal

Source(s): PLoS Genetics. Jan2013, Vol. 9 Issue 1, p1-18. 18p. 1 Diagram, 3 Charts, 7 Graphs.

Abstract: In the past few years, case-control studies of common diseases have shifted their focus from single genes to whole exomes. New sequencing technologies now routinely detect hundreds of thousands of sequence variants in a single study, many of which are ...