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A Hybrid Likelihood Model for Sequence-Based Disease Association Studies.

Publication Type: Academic Journal

Source(s): PLoS Genetics; Jan2013, Vol. 9 Issue 1, p1-18, 18p, 1 Diagram, 3 Charts, 7 Graphs

Abstract: Copyright of PLoS Genetics is the property of Public Library of Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download...

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A hybrid likelihood model for sequence-based disease association studies.

Publication Type: Academic Journal

Source(s): PLoS genetics [PLoS Genet] 2013; Vol. 9 (1), pp. e1003224. Date of Electronic Publication: 2013 Jan 24.

Abstract: In the past few years, case-control studies of common diseases have shifted their focus from single genes to whole exomes. New sequencing technologies now routinely detect hundreds of thousands of sequence variants in a single study, many of which are ...

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