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Advanced Search Results For "PARLA, JAMES"

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 "PARLA, JAMES"
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Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

Publication Type: Academic Journal

Source(s): Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 May 01; Vol. 115 (18), pp. 4767-4772. Date of Electronic Publication: 2018 Apr 18.

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Abstract: To evaluate whether germline variants in genes encoding pancreatic secretory enzymes contribute to pancreatic cancer susceptibility, we sequenced the coding regions of CPB1 and other genes encoding pancreatic secretory enzymes and known pancreatitis su...

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Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

Publication Type: Academic Journal

Source(s): Cancer discovery [Cancer Discov] 2016 Feb; Vol. 6 (2), pp. 166-75. Date of Electronic Publication: 2015 Dec 09.

Abstract: Unlabelled: Pancreatic cancer is projected to become the second leading cause of cancer-related death in the United States by 2020. A familial aggregation of pancreatic cancer has been established, but the cause of this aggregation in most families is ...

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