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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026
Publication Type: Academic Journal
Source(s): The Lancet Global Health, Vol 11, Iss 3, Pp e385-e413 (2023)
Abstract: Summary: Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, e...
An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1
Publication Type: Academic Journal
Source(s): BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract: Abstract Background Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be used to modulate processe...
CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity
Publication Type: Academic Journal
Source(s): BMC Genetics, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract: Abstract Background The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF occ...
CGGBP1 regulates CTCF occupancy at repeats
Publication Type: Academic Journal
Source(s): Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-22 (2019)
Abstract: Abstract Background CGGBP1 is a repeat-binding protein with diverse functions in the regulation of gene expression, cytosine methylation, repeat silencing and genomic integrity. CGGBP1 has also been identified as a cooperator of histone-modifying enzym...
Dynamic bimodal changes in CpG and non-CpG methylation genome-wide upon CGGBP1 loss-of-function
Publication Type: Academic Journal
Source(s): BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract: Abstract Objectives Although CpG methylation is well studied, mechanisms of non-CpG methylation in mammals remains elusive. Studying proteins with non-CpG cytosine methylation-sensitive DNA-binding, such as human CGGBP1, can unveil cytosine methylation...
Role of de novo DQ donor-specific antibody in antibody-mediated rejection in renal transplant recipient: A case study
Publication Type: Academic Journal
Source(s): Asian Journal of Transfusion Science, Vol 13, Iss 2, Pp 136-139 (2019)
Abstract: The human leukocyte antigen (HLA) matching plays an important role in determining the clinical outcome of renal transplantation. The development of donor specific antibodies (DSA) against HLA is associated with antibody mediated allograft tissue injury...
Distinct DNA Sequence Preference for Histone Occupancy in Primary and Transformed Cells
Publication Type: Academic Journal
Source(s): Cancer Informatics, Vol 18 (2019)
Abstract: Genome-wide occupancy of several histone modifications in various cell types has been studied using chromatin immunoprecipitation (ChIP) sequencing. Histone occupancy depends on DNA sequence features like inter-strand symmetry of base composition and p...
A Readability Analysis of Online Cardiovascular Disease-Related Health Education Materials
Publication Type: Academic Journal
Source(s): Health Literacy Research and Practice, Vol 3, Iss 2, Pp e75-e80 (2019)
Abstract: Background: Online cardiovascular health materials are easily accessible with an Internet connection, but the readability of its content may limit practical use by patients. Objective: The goal of our study was to assess the readability of the most co...
Synthesis of cyclic α-pinane carbonate – a potential monomer for bio-based polymers.
Publication Type: Academic Journal
Source(s): RSC Advances; 2022, Vol. 12 Issue 27, p17454-17465, 12p
CGGBP1-dependent CTCF-binding sites restrict ectopic transcription.
Publication Type: Academic Journal
Source(s): Cell Cycle; Nov2021, Vol. 20 Issue 22, p2387-2401, 15p
Abstract: Copyright of Cell Cycle is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or ema...