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Advanced Search Results For "Pedersen, Brian"

1 - 10 of 911 results for
 "Pedersen, Brian"
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Publication Type: Academic Journal

Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)

Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...

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Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes

Publication Type: Academic Journal

Source(s): Frontiers in Immunology, Vol 13 (2022)

Abstract: Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption. Metabolic changes in fibroblast-like synoviocytes (FLS) likely contribute to FLS abnormal response and strongly contribute to joint destruction. These chan...

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Mechanochemistry of Phosphorus and Arsenic Alloys for Visible and Infrared Photonics

Publication Type: Academic Journal

Source(s): Advanced Photonics Research, Vol 3, Iss 9, Pp n/a-n/a (2022)

Abstract: Incorporating few‐layer 2D phosphorus–arsenic alloys (PAs) into optoelectronic devices requires a synthesis technique that allows control of the alloy composition while producing volumes of material suitable for application development such as photodet...

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Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation

Publication Type: Academic Journal

Source(s): Frontiers in Pharmacology, Vol 13 (2022)

Abstract: Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for ALI are limited; identifying novel concepts in treatment is essent...

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Clinical presentation and cardiac imaging findings in patient cases of perimyocarditis and pericarditis with a temporal association to SARS-CoV-2 vaccination

Publication Type: Academic Journal

Source(s): Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Abstract: AimsWe aimed to investigate and present cases of perimyocarditis and pericarditis verified by cardiovascular resonance (CMR) imaging in patients with a strong temporal association to SARS-CoV-2 vaccination. We sought to describe the clinical presentati...

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Incidence rates of dilated cardiomyopathy in adult first-degree relatives versus matched controls

Publication Type: Academic Journal

Source(s): International Journal of Cardiology: Heart & Vasculature, Vol 41, Iss , Pp 101065- (2022)

Abstract: Background: The incidence rates and importance of traditional risk factors in dilated cardiomyopathy among first-degree relatives are unknown. Methods and Results: We identified all probands with dilated cardiomyopathy (n = 13,714, mean age at diagnosi...

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Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Abstract: Penetrance of variants in monogenic disease and clinical utility of common polygenic variation has not been well explored on a large-scale. Here, the authors use exome sequencing data from 77,184 individuals to generate penetrance estimates and assess ...

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Heart failure associated with imported malaria: a nationwide Danish cohort study

Publication Type: Academic Journal

Source(s): ESC Heart Failure, Vol 8, Iss 5, Pp 3521-3529 (2021)

Abstract: Abstract Aims Despite adequate treatment, recent studies have hypothesized that malaria may affect long‐term cardiovascular function. We aimed to investigate the long‐term risk of cardiovascular events and death in individuals with a history of importe...

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Flu Vaccine and Mortality in Hypertension: A Nationwide Cohort Study

Publication Type: Academic Journal

Source(s): Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 6 (2022)

Abstract: Background Influenza infection may increase the risk of stroke and acute myocardial infarction (AMI). Whether influenza vaccination may reduce mortality in patients with hypertension is currently unknown. Methods and Results We performed a nationwide c...

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