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NEUROlogical Prognosis After Cardiac Arrest in Kids (NEUROPACK) study: protocol for a prospective multicentre clinical prediction model derivation and validation study in children after cardiac arrest
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 10, Iss 9 (2020)
Abstract: Introduction Currently, we are unable to accurately predict mortality or neurological morbidity following resuscitation after paediatric out of hospital (OHCA) or in-hospital (IHCA) cardiac arrest. A clinical prediction model may improve communication ...
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Publication Type: Academic Journal
Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)
Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...
A declaração PRISMA 2020: diretriz atualizada para relatar revisões sistemáticas
Publication Type: Academic Journal
Source(s): Revista Panamericana de Salud Pública, Vol 46, Iss 112, Pp 1-12 (2022)
Abstract: A declaração dos Principais Itens para Relatar Revisões Sistemáticas e Meta-análises (PRISMA), publicada em 2009, foi desenvolvida para ajudar revisores sistemáticos a relatar de forma transparente por que a revisão foi feita, os métodos empregados e o...
Conserved signalling components coordinate epidermal patterning and cuticle deposition in barley
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract: The leaf epidermis is sealed by a lipid-rich cuticle to prevent water loss and interspersed with stomatal pores to allow gas exchange. Here the authors provide evidence that two barley proteins, HvYDA1 and HvBRX-Solo, regulate both processes linking ep...
Annotating very high-resolution satellite imagery: A whale case study
Publication Type: Academic Journal
Source(s): MethodsX, Vol 10, Iss , Pp 102040- (2023)
Abstract: The use of very high-resolution (VHR) optical satellites is gaining momentum in the field of wildlife monitoring, particularly for whales, as this technology is showing potential for monitoring the less studied regions. However, surveying large areas u...
Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy
Publication Type: Academic Journal
Source(s): Trials, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract: Abstract Background Mitochondrial disease is a heterogenous group of rare, complex neurometabolic disorders. Despite their individual rarity, collectively mitochondrial diseases represent the most common cause of inherited metabolic disorders in the UK...
European Registry of Materials: global, unique identifiers for (undisclosed) nanomaterials
Publication Type: Academic Journal
Source(s): Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract: Abstract Management of nanomaterials and nanosafety data needs to operate under the FAIR (findability, accessibility, interoperability, and reusability) principles and this requires a unique, global identifier for each nanomaterial. Existing identifier...
The health, cost and equity impacts of restrictions on the advertisement of high fat, salt and sugar products across the transport for London network: a health economic modelling study
Publication Type: Academic Journal
Source(s): International Journal of Behavioral Nutrition and Physical Activity, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract: Abstract Background Policies aimed at restricting the marketing of high fat, salt and sugar products have been proposed as one way of improving population diet and reducing obesity. In 2019, Transport for London implemented advertising restrictions on ...
Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 12, Iss 11 (2022)
Abstract: Objectives Hospital-acquired pressure injuries (PIs) are a source of morbidity and mortality, and many are potentially preventable.Design This study prospectively evaluated the prevalence and the associated factors of PIs in adult critical care patient...
Compound dominant-null heterozygosity in a family with RP1-related retinal dystrophy
Publication Type: Academic Journal
Source(s): American Journal of Ophthalmology Case Reports, Vol 28, Iss , Pp 101698- (2022)
Abstract: Purpose: To report on the presence of autosomal dominant and compound dominant-null RP1-related retinitis pigmentosa in the same non-consanguineous family. Observation: The father was minimally symptomatic and referred by his optometrist aged 38. He wa...