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Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity
Publication Type: Academic Journal
Source(s): BMJ Paediatrics Open, Vol 6, Iss 1 (2022)
Abstract: Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify...
Genome‐Wide Association Study of NAFLD Using Electronic Health Records
Publication Type: Academic Journal
Source(s): Hepatology Communications, Vol 6, Iss 2, Pp 297-308 (2022)
Abstract: Genome‐wide association studies (GWAS) have identified several risk loci for nonalcoholic fatty liver disease (NAFLD). Previous studies have largely relied on small sample sizes and have assessed quantitative traits. We performed a case‐control GWAS in...
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study
Publication Type: Academic Journal
Source(s): The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)
Abstract: Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Publication Type: Academic Journal
Source(s): The Lancet Global Health, Vol 10, Iss 7, Pp e1003-e1011 (2022)
Abstract: Summary: Background: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of ...
Remote diagnosis of surgical-site infection using a mobile digital intervention: a randomised controlled trial in emergency surgery patients
Publication Type: Academic Journal
Source(s): npj Digital Medicine, Vol 4, Iss 1, Pp 1-9 (2021)
Abstract: Abstract Surgical site infections (SSI) cause substantial morbidity and pose a burden to acute healthcare services after surgery. We aimed to investigate whether a smartphone-delivered wound assessment tool can expedite diagnosis and treatment of SSI a...
Identifying cell-enriched miRNAs in kidney injury and repair
Publication Type: Academic Journal
Source(s): JCI Insight, Vol 5, Iss 24 (2020)
Abstract: Small noncoding RNAs, miRNAs (miRNAs), are emerging as important modulators in the pathogenesis of kidney disease, with potential as biomarkers of kidney disease onset, progression, or therapeutic efficacy. Bulk tissue small RNA-sequencing (sRNA-Seq) a...
Selective non-operative management of penetrating abdominal injuries at Northern European trauma centers: the NordiPen Study.
Publication Type: Academic Journal
Source(s): European Journal of Trauma & Emergency Surgery; Jun2022, Vol. 48 Issue 3, p2023-2027, 5p, 1 Diagram, 2 Charts
Abstract: Copyright of European Journal of Trauma & Emergency Surgery is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, us...
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study
Publication Type: Periodical
Source(s): The Lancet Digital Health; April 2022, Vol. 4 Issue: 4 pe220-e234, 15p
Abstract: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial publication on...
Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol.
Publication Type: Academic Journal
Source(s): Thorax; Jun2022, Vol. 77 Issue 6, p606-615, 10p
Genome‐wide analysis identifies gallstone‐susceptibility loci including genes regulating gastrointestinal motility.
Publication Type: Academic Journal
Source(s): Hepatology (02709139); May2022, Vol. 75 Issue 5, p1081-1094, 14p