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Advanced Search Results For "Potter, Claire"

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 "Potter, Claire"
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Venetoclax combined with low dose cytarabine compared to standard of care intensive chemotherapy for the treatment of favourable risk adult acute myeloid leukaemia (VICTOR): Study protocol for an international, open-label, multicentre, molecularly-guided randomised, phase II trial

Publication Type: Academic Journal

Source(s): BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract: Abstract Background For patients with acute myeloid leukaemia (AML), the only potentially curative treatment is intensive chemotherapy (IC). This is highly toxic, particularly for patients > 60 years, potentially leading to prolonged hospitalisations r...

Clinical indications and triaging for adult transthoracic echocardiography: a consensus statement by the British Society of Echocardiography in collaboration with British Heart Valve Society

Publication Type: Academic Journal

Source(s): Echo Research and Practice, Vol 9, Iss 1, Pp 1-16 (2022)

Abstract: Abstract Transthoracic echocardiography (TTE) is widely utilised within many aspects of clinical practice, as such the demand placed on echocardiography services is ever increasing. In an attempt to provide incremental value for patients and standardis...

Translating principles of precision medicine into speech-language pathology: Clinical trial of a proactive speech and language intervention for infants with classic galactosemia

Publication Type: Academic Journal

Source(s): HGG Advances, Vol 3, Iss 3, Pp 100119- (2022)

Abstract: Summary: Precision medicine is an emerging approach to managing disease by taking into consideration an individual’s genetic and environmental profile toward two avenues to improved outcomes: prevention and personalized treatments. This framework is la...

Acute and early developmental outcomes of children with Duarte galactosemia

Publication Type: Academic Journal

Source(s): JIMD Reports, Vol 63, Iss 1, Pp 101-106 (2022)

Abstract: Abstract A recent study demonstrated that children with Duarte galactosemia (DG) do not show increased prevalence of detectable developmental complications when 6–12 years old. However, that study left unanswered whether infants with DG might be at inc...

Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Abstract: Here, the authors describe the emergence and spread of a new potential SARS-CoV-2 variant of interest, B.1.620. They show that this lineage, first identified in Lithuania, has established local transmission in Europe on multiple occasions and likely em...


Is more better? An analysis of toxicity and response outcomes from dose-finding clinical trials in cancer

Publication Type: Academic Journal

Source(s): BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)

Abstract: Abstract Background The overwhelming majority of dose-escalation clinical trials use methods that seek a maximum tolerable dose, including rule-based methods like the 3+3, and model-based methods like CRM and EWOC. These methods assume that the inciden...

Exposure to the troubles in Northern Ireland, memory functioning, and social activity engagement: results from NICOLA.

Publication Type: Academic Journal

Source(s): European Journal of Ageing; Dec2022, Vol. 19 Issue 4, p1099-1109, 11p

Abstract: Copyright of European Journal of Ageing is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downl...

A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 11, Iss 7 (2021)

Abstract: Introduction The improvements in short-term outcome after severe trauma achieved through early resuscitation and acute care can be offset over the following weeks by an acute systemic inflammatory response with immuneparesis leading to infection, multi...


Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

Publication Type: Academic Journal

Source(s): Contemporary Clinical Trials Communications, Vol 22, Iss , Pp 100787- (2021)

Abstract: Introduction: Cluster randomized crossover trials are often faced with a dilemma when selecting an optimal model of consent, as the traditional model of obtaining informed consent from participant's before initiating any trial related activities may no...