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Advanced Search Results For "Quinn, Mary Ellen"

1 - 10 of 3,498 results for
 "Quinn, Mary Ellen"
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Teaching Primary Prevention of Alzheimer’s Disease

Publication Type:Academic Journal

Source(s):Journal of Primary Care & Community Health, Vol 1 (2010)

Abstract:Alzheimer’s disease (AD) is one of the most feared illnesses among older adults. Although no cure exists, an emerging body of literature has outlined potentially risk-reducing behaviors. As evidence has become available on risk reduction, community org...

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Prediction and Classification of Alzheimer’s Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers

Publication Type:Academic Journal

Source(s):Frontiers in Computational Neuroscience, Vol 13 (2019)

Abstract:Alzheimer's disease (AD), including its mild cognitive impairment (MCI) phase that may or may not progress into the AD, is the most ordinary form of dementia. It is extremely important to correctly identify patients during the MCI stage because this is...

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The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 11 (2019)

Abstract:Mild cognitive impairment (MCI) is a transitional state between the cognitive changes in normal aging and Alzheimer’s disease (AD), which induces abnormalities in specific brain regions. Previous studies showed that paired helical filaments Tau (PHF-Ta...

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New Perspective for Non-invasive Brain Stimulation Site Selection in Mild Cognitive Impairment: Based on Meta- and Functional Connectivity Analyses

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 11 (2019)

Abstract:BackgroundNon-invasive brain stimulation (NIBS) has been widely used to treat mild cognitive impairment (MCI). However, there exists no consensus on the best stimulation sites.ObjectiveTo explore potential stimulation locations for NIBS treatment in pa...

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Performing Sparse Regularization and Dimension Reduction Simultaneously in Multimodal Data Fusion

Publication Type:Academic Journal

Source(s):Frontiers in Neuroscience, Vol 13 (2019)

Abstract:Collecting multiple modalities of neuroimaging data on the same subject is increasingly becoming the norm in clinical practice and research. Fusing multiple modalities to find related patterns is a challenge in neuroimaging analysis. Canonical correlat...

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Quantitative 18F-AV1451 Brain Tau PET Imaging in Cognitively Normal Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease Patients

Publication Type:Academic Journal

Source(s):Frontiers in Neurology, Vol 10 (2019)

Abstract:Recent developments of tau Positron Emission Tomography (PET) allows assessment of regional neurofibrillary tangles (NFTs) deposition in human brain. Among the tau PET molecular probes, 18F-AV1451 is characterized by high selectivity for pathologic tau...

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Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 213-226.e3 (2018)

Abstract:Summary: Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer types from The Cance...

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Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 23, Iss 1, Pp 297-312.e12 (2018)

Abstract:Summary: Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer pathways, oncogenes, and tumor suppressors (cancer genes) b...

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