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Oncology Drug Effectiveness from Electronic Health Record Data Calibrated Against RCT Evidence: The PARSIFAL Trial Emulation
Publication Type: Academic Journal
Source(s): Clinical Epidemiology, Vol Volume 14, Pp 1135-1144 (2022)
Abstract: David Merola,1,2 Jessica Young,2,3 Deborah Schrag,4 Kueiyu Joshua Lin,1,2,5 Nicholas Robert,6 Sebastian Schneeweiss1,2 1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School...
Development and Validation of a Healthcare Utilization-Based Algorithm to Identify Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Publication Type: Academic Journal
Source(s): International Journal of COPD, Vol Volume 16, Pp 1687-1698 (2021)
Abstract: Douglas W Mapel,1,* Melissa H Roberts,1,* Susan Sama,2 Priyanka J Bobbili,3 Wendy Y Cheng,3 Mei Sheng Duh,3 Catherine Nguyen,3 Philippe Thompson-Leduc,3 Melissa K Van Dyke,4 Kieran J Rothnie,4 Devi Sundaresan,2 Julia M Certa,5 Thomas S Whiting,5 Jennif...
Impact of COVID-19 on non-COVID intensive care unit service utilization, case mix and outcomes: A registry-based analysis from India [version 2; peer review: 2 approved]
Publication Type: Academic Journal
Source(s): Wellcome Open Research, Vol 6 (2021)
Abstract: Background: Coronavirus disease 2019 (COVID-19) has been responsible for over 3.4 million deaths globally and over 25 million cases in India. As part of the response, India imposed a nation-wide lockdown and prioritized COVID-19 care in hospitals and i...
Shape of the OGTT glucose response curve: relationship with β-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin
Publication Type: Academic Journal
Source(s): BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65): protocol and statistical analysis plan for a randomised clinical trial
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 10, Iss 11 (2020)
Abstract: Introduction Vasodilatory hypotension is common among intensive care unit (ICU) patients; vasopressors are considered standard of care. However, optimal mean arterial pressure (MAP) targets for vasopressor titration are unknown. The objective of the Op...
Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study
Publication Type: Academic Journal
Source(s): The Lancet Global Health, Vol 7, Iss 4, Pp e513-e522 (2019)
Abstract: Summary: Background: Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal and neonatal outcomes. Methods: A 7-day, international, prospe...
Corticosteroid Therapy in Critical Illness due to Seasonal and Pandemic Influenza
Publication Type: Academic Journal
Source(s): Canadian Respiratory Journal, Vol 22, Iss 5, Pp 271-274 (2015)
Abstract: BACKGROUND: Survey data suggest that Canadian intensivists administer corticosteroids to critically ill patients primarily in response to airway obstruction, perceived risk for adrenal insufficiency and hemodynamic instability.
Association of Intra-Operative Metaphyseal Fractures with Prosthesis Size during Hemiarthroplasty of the Hip
Publication Type: Academic Journal
Source(s): Journal of Orthopaedic Surgery, Vol 16 (2008)
Abstract: Purpose. To study the possible causes of intra-operative metaphyseal fractures in elderly patients undergoing hemiarthroplasty for displaced intracapsular femoral neck fracture. Methods. 36 men and 228 women aged 61 to 89 years with 273 displaced femor...
Critical care resources in the Solomon Islands: a cross-sectional survey
Publication Type: Academic Journal
Source(s): BMC International Health and Human Rights, Vol 12, Iss 1, p 1 (2012)
Abstract: Abstract Background There are minimal data available on critical care case-mix, care processes and outcomes in lower and middle income countries (LMICs). The objectives of this paper were to gather data in the Solomon Islands in order to gain a better ...
An innovative telemedicine knowledge translation program to improve quality of care in intensive care units: protocol for a cluster randomized pragmatic trial
Publication Type: Academic Journal
Source(s): Implementation Science, Vol 4, Iss 1, p 5 (2009)
Abstract: Abstract Background There are challenges to timely adoption of, and ongoing adherence to, evidence-based practices known to improve patient care in the intensive care unit (ICU). Quality improvement initiatives using a collaborative network approach ma...