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Advanced Search Results For "Roger Douglas"

1 - 10 of 3,358 results for
 "Roger Douglas"
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Functional, imaging, and respiratory evaluation (FIRE) of patients post-hospitalization for COVID-19: protocol for a pilot observational study

Publication Type:Academic Journal

Source(s):Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-10 (2022)

Abstract:Abstract Introduction We describe a protocol for FIRE CORAL, an observational cohort study that examines the recovery from COVID-19 disease following acute hospitalization with an emphasis on functional, imaging, and respiratory evaluation. Methods and...

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Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Abstract:There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using admix...

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Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF

Publication Type:Academic Journal

Source(s):Open Heart, Vol 9, Iss 2 (2022)

Abstract:Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. We examine the influence of BMI on outcomes and whether this is modi...

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Breast cancer risks associated with missense variants in breast cancer susceptibility genes

Publication Type:Academic Journal

Source(s):Genome Medicine, Vol 14, Iss 1, Pp 1-17 (2022)

Abstract:Abstract Background Protein truncating variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2 are associated with increased breast cancer risk, but risks associated with missense variants in these genes are uncertain. Methods We analyzed data on 59,639 breast...

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PROTOCOL: Digital interventions to reduce social isolation and loneliness in older adults: An evidence and gap map

Publication Type:Academic Journal

Source(s):Campbell Systematic Reviews, Vol 18, Iss 3, Pp n/a-n/a (2022)

Abstract:Abstract This is the protocol for a Campbell systematic review. The objectives are as follows: the aim is to map available evidence on the effects of digital interventions to mitigate social isolation and/or loneliness in older adults in all settings e...

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Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

Publication Type:Academic Journal

Source(s):EBioMedicine, Vol 83, Iss , Pp 104208- (2022)

Abstract:Summary: Background: Better understanding of the association between characteristics of patients hospitalized with coronavirus disease 2019 (COVID-19) and outcome is needed to further improve upon patient management. Methods: Immunophenotyping Assessme...

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HPLC-DAD-ESI-MS profile, antibacterial activity, and modulation of the activity of antibiotics by Carica papaya L. against Escherichia coli serotypes

Publication Type:Academic Journal

Source(s):Phytomedicine Plus, Vol 2, Iss 3, Pp 100306- (2022)

Abstract:Background: Diarrhea is currently the second leading cause of death among children under five years old in the world and therefore, remains a global public health problem. Considering that most cases of diarrhea are due to gastrointestinal infections, ...

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Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci

Publication Type:Academic Journal

Source(s):Breast Cancer Research, Vol 24, Iss 1, Pp 1-15 (2022)

Abstract:Abstract Background Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with breast cancer risk. Twin studies suggest that MD phenotypes are highly heritab...

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Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract:Abstract Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. We conducted a genome-wide interaction analysis b...

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Performance of anterior nares and tongue swabs for nucleic acid, Nucleocapsid, and Spike antigen testing for detecting SARS-CoV-2 against nasopharyngeal PCR and viral culture

Publication Type:Academic Journal

Source(s):International Journal of Infectious Diseases, Vol 117, Iss , Pp 287-294 (2022)

Abstract:Objectives: This study assesses and compares the performance of different swab types and specimen collection sites for SARS-CoV-2 testing, to reference standard real-time reverse transcriptase-polymerase chain reaction (RT-PCR) and viral culture. Metho...

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