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Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract: Sarcomas are rare tumours with many different subtypes and clinical outcomes; a broader knowledge of their genetic features is required. Here, the authors analyse 2138 soft tissue and bone sarcomas across 45 subtypes using MSK-IMPACT targeted sequencin...
Trauma-informed care for youth suicide prevention: A qualitative analysis of caregivers' perspectives.
Publication Type: Academic Journal
Source(s): Psychological Trauma: Theory, Research, Practice & Policy; May2022, Vol. 14 Issue 4, p653-660, 8p
Rhizopus Keratitis Associated with Poor Contact Lens Hygiene
Publication Type: Academic Journal
Source(s): Case Reports in Ophthalmology, Vol 7, Iss 1, Pp 21-24 (2016)
Abstract: We report a case of Rhizopus keratitis in a young woman with poor contact lens hygiene. The mold was highly sensitive to treatment with amphotericin 0.15% drops, after a relatively prompt diagnosis. Obtaining cultures of both corneal infiltrates and pr...
Mismatches in scale between highly mobile marine megafauna and marine protected areas
Publication Type: Academic Journal
Source(s): Frontiers in Marine Science, Vol 9 (2022)
Abstract: Marine protected areas (MPAs), particularly large MPAs, are increasing in number and size around the globe in part to facilitate the conservation of marine megafauna under the assumption that large-scale MPAs better align with vagile life histories; ho...
Timing of Intubation in Coronavirus Disease 2019: A Study of Ventilator Mechanics, Imaging, Findings, and Outcomes
Publication Type: Academic Journal
Source(s): Critical Care Explorations, Vol 3, Iss 5, p e0415 (2021)
Abstract: Objectives:. Determine the variation in outcomes and respiratory mechanics between the subjects who are intubated earlier versus later in their coronavirus disease 2019 course. Design:. Retrospective cohort study. Setting:. Northwestern Memorial Hospit...
Stress-related dysfunction of the right inferior frontal cortex in high ruminators: An fNIRS study
Publication Type: Academic Journal
Source(s): NeuroImage: Clinical, Vol 18, Iss , Pp 510-517 (2018)
Abstract: Repetitive thinking styles such as rumination are considered to be a key factor in the development and maintenance of mental disorders. Different situational triggers (e.g., social stressors) have been shown to elicit rumination in subjects exhibiting ...
Aberrant functional connectivity in depression as an index of state and trait rumination
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract: Abstract Depression has been shown to be related to a variety of aberrant brain functions and structures. Particularly the investigation of alterations in functional connectivity (FC) in major depressive disorder (MDD) has been a promising endeavor, si...
A Community Call to Action: Use of Quality Improvement Strategies to Address Youth Suicides
Publication Type: Periodical
Source(s): Evidence-Based Practice in Child and Adolescent Mental Health; July 2021, Vol. 6 Issue: 3 p328-342, 15p
Abstract: ABSTRACTYouth suicide clusters are a tragedy that no community should have to face. This paper details how a large community came together to better understand and prevent the future loss of young lives in their County using interdisciplinary quality i...
Colorimetric approach to high-throughput mutation analysis
Publication Type: Academic Journal
Source(s): BioTechniques, Vol 38, Iss 4, Pp 635-639 (2005)
Abstract: High-throughput genomic mutation screening for primary tumors has characteristically been expensive, labor-intensive, and inadequate to detect low levels of mutation in a background of wild-type signal. We present a new, combined PCR and colorimetric a...
Quality Improvement for Acute Trauma-Informed Suicide Prevention Care: Introduction to Special Issue
Publication Type: Periodical
Source(s): Evidence-Based Practice in Child and Adolescent Mental Health; July 2021, Vol. 6 Issue: 3 p303-306, 4p