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Advanced Search Results For "Rubenstein L"

1 - 10 of 3,247 results for
 "Rubenstein L"
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LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants

Publication Type:Academic Journal

Source(s):Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-11 (2022)

Abstract:Abstract Background Tbr1 encodes a T-box transcription factor and is considered a high confidence autism spectrum disorder (ASD) gene. Tbr1 is expressed in the postmitotic excitatory neurons of the deep neocortical layers 5 and 6. Postnatally and neona...

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Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain

Publication Type:Academic Journal

Source(s):Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)

Abstract:Abstract Background Genetic variants in the voltage-gated sodium channels SCN1A, SCN2A, SCN3A, and SCN8A are leading causes of epilepsy, developmental delay, and autism spectrum disorder. The mRNA splicing patterns of all four genes vary across develop...

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Assessment of the Chad guinea worm surveillance information system: A pivotal foundation for eradication.

Publication Type:Academic Journal

Source(s):PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009675 (2021)

Abstract:BackgroundIn the absence of a vaccine or pharmacological treatment, prevention and control of Guinea worm disease is dependent on timely identification and containment of cases to interrupt transmission. The Chad Guinea Worm Eradication Program (CGWEP)...

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Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons

Publication Type:Academic Journal

Source(s):Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)

Abstract:Dong Won Kim and colleagues investigate the mechanisms by which hypothalamic GABAergic neurons differentiate during development. They report that Lhx6 is crucial for the survival of hypothalamic neurons.

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A Global Survey on Changes in the Supply, Price, and Use of Illicit Drugs and Alcohol, and Related Complications During the 2020 COVID-19 Pandemic

Publication Type:Academic Journal

Source(s):Frontiers in Psychiatry, Vol 12 (2021)

Abstract:Background and Aims: COVID-19 has infected more than 77 million people worldwide and impacted the lives of many more, with a particularly devastating impact on vulnerable populations, including people with substance use disorders (SUDs). Quarantines, t...

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Change in Micronutrient Intake among People with Relapsing-Remitting Multiple Sclerosis Adapting the Swank and Wahls Diets: An Analysis of Weighed Food Records

Publication Type:Academic Journal

Source(s):Nutrients, Vol 13, Iss 3507, p 3507 (2021)

Abstract:The low-saturated fat (Swank) and modified Paleolithic elimination (Wahls) diets have shown promise for MS symptoms; however, due to their restriction of specific foods, inadequate intake of micronutrients is concerning. Therefore, as part of a randomi...

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Community-based Guinea worm surveillance in Chad: Evaluating a system at the intersection of human and animal disease.

Publication Type:Academic Journal

Source(s):PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009285 (2021)

Abstract:BackgroundGuinea worm is a debilitating parasitic infection targeted for eradication. Annual human cases have dropped from approximately 3,500,000 in 1986 to 54 in 2019. Recent identification of canine cases in Chad threatens progress, and therefore de...

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Reorganization of Substance Use Treatment and Harm Reduction Services During the COVID-19 Pandemic: A Global Survey

Publication Type:Academic Journal

Source(s):Frontiers in Psychiatry, Vol 12 (2021)

Abstract:Background: The coronavirus disease 2019 (COVID-19) pandemic has impacted people with substance use disorders (SUDs) worldwide, and healthcare systems have reorganized their services in response to the pandemic.Methods: One week after the announcement ...

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Do empirical observations support commonly-held climate change range shift hypotheses? A systematic review protocol

Publication Type:Academic Journal

Source(s):Environmental Evidence, Vol 9, Iss 1, Pp 1-10 (2020)

Abstract:Abstract Background Among the most widely anticipated climate-related impacts to biodiversity are geographic range shifts, whereby species shift their spatial distribution in response to changing climate conditions. In particular, a series of commonly ...

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Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging

Publication Type:Academic Journal

Source(s):International Journal of Biomedical Imaging, Vol 2021 (2021)

Abstract:Cardiac magnetic resonance imaging (CMR) is considered the gold standard for measuring cardiac function. Further, in a single CMR exam, information about cardiac structure, tissue composition, and blood flow could be obtained. Nevertheless, CMR is unde...

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