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Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences, Vol 23, Iss 12680, p 12680 (2022)
Abstract: Obesity impacts 650 million individuals globally, often co-occurring with metabolic syndrome. Though many obese individuals experience metabolic abnormalities (metabolically unhealthy obese [MUO]), ~30% do not (metabolically healthy obese [MHO]). Conve...
Diet impacts triple‐negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin‐mediated cardiac dysfunction
Publication Type: Academic Journal
Source(s): Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract: Abstract Anthracyclines are standard‐of‐care chemotherapy for the treatment of triple‐negative breast cancer (TNBC). However, high anthracyclines cumulative doses increase heart failure risk. Designing therapeutic strategies that ameliorate cardiac tox...
Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence.
Publication Type: Academic Journal
Source(s): GeroScience; Feb2023, Vol. 45 Issue 1, p507-521, 15p
Abstract: Copyright of GeroScience is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email a...
Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity
Publication Type: Academic Journal
Source(s): Frontiers in Nutrition, Vol 8 (2021)
Abstract: Over 650 million adults are obese (body mass index ≥ 30 kg/m2) worldwide. Obesity is commonly associated with several comorbidities, including cardiovascular disease and type II diabetes. However, compiled estimates suggest that from 5 to 40% of obese ...
Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences; Oct2022, Vol. 23 Issue 20, p12680-N.PAG, 18p
Abstract: Copyright of International Journal of Molecular Sciences is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print,...
Type-2 Diabetes as a Risk Factor for Severe COVID-19 Infection
Publication Type: Academic Journal
Source(s): Microorganisms, Vol 9, Iss 1211, p 1211 (2021)
Abstract: The current outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), termed coronavirus disease 2019 (COVID-19), has generated a notable challenge for diabetic patients. Overall, people with diabetes have a higher risk of develo...
Diet impacts triple‐negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin‐mediated cardiac dysfunction.
Publication Type: Academic Journal
Source(s): Physiological Reports; Apr2022, Vol. 10 Issue 8, p1-15, 15p
Abstract: Copyright of Physiological Reports is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, ...
Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates.
Publication Type: Academic Journal
Source(s): American Journal of Physiology: Heart & Circulatory Physiology; Mar2022, Vol. 322 Issue 3, pH474-H485, 12p
Abstract: Copyright of American Journal of Physiology: Heart & Circulatory Physiology is the property of American Physiological Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express ...
Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence
Publication Type: Periodical
Source(s): GeroScience; 20220101, Issue: Preprints p1-15, 15p
Abstract: The pathogenesis of many age-related diseases is linked to cellular senescence, a state of inflammation-inducing, irreversible cell cycle arrest. The consequences and mechanisms of age-associated cellular senescence are often studied using in vivo mode...
Skeletal muscle extracellular matrix remodeling with worsening glycemic control in nonhuman primates.
Publication Type: Academic Journal
Source(s): American Journal of Physiology: Regulatory, Integrative & Comparative Physiology; Mar2021, Vol. 320 Issue 3, pR226-R235, 10p
Abstract: Copyright of American Journal of Physiology: Regulatory, Integrative & Comparative Physiology is the property of American Physiological Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright...