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Advanced Search Results For "SHIMIZU, Kosuke"

1 - 10 of 964 results for
 "SHIMIZU, Kosuke"
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The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)

Abstract:Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splic...

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The effect of positive autobiographical memory retrieval on decision-making under risk: A computational model-based analysis

Publication Type:Academic Journal

Source(s):Frontiers in Psychiatry, Vol 13 (2022)

Abstract:Psychiatric disorders such as depressive and anxiety disorders are associated with altered decision-making under risk. Recent advances in neuroeconomics and computational psychiatry have further discomposed risk-based decision-making into distinct cogn...

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Clinical use of expanded prostate cancer index composite-based health-related quality of life outcomes after robot-assisted radical prostatectomy for localized prostate cancer

Publication Type:Academic Journal

Source(s):Prostate International, Vol 10, Iss 1, Pp 62-67 (2022)

Abstract:Background: This study aimed to assess the longitudinal health-related quality of life (HRQOL) using the Expanded Prostate Cancer Index Composite (EPIC) and HRQOL change between the nerve-sparing technique in Japanese men treated with robot-assisted ra...

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Spatial distribution of live gut microbiota and bile acid metabolism in various parts of human large intestine

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)

Abstract:Abstract Gut microbiomics is based on analysis of both live and dead cells in the stool. However, to understand the ecology of gut microbiota and their symbiotic relationships with hosts, spatial distribution of live bacteria must be examined. Here, we...

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Effects of artificial nutrition and hydration on survival in patients with head and neck cancer and esophageal cancer admitted to palliative care units

Publication Type:Academic Journal

Source(s):Clinical Nutrition Open Science, Vol 41, Iss , Pp 33-43 (2022)

Abstract:Summary: Background: The benefits of artificial nutrition and hydration in patients with head and neck cancer and esophageal cancer in the late stage remain unknown. We performed a secondary analysis of a cohort study to investigate the effects of ente...

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Mucin‐producing urothelial‐type adenocarcinoma of the prostate diagnosed after robot‐assisted radical prostatectomy

Publication Type:Academic Journal

Source(s):IJU Case Reports, Vol 5, Iss 1, Pp 32-35 (2022)

Abstract:Introduction Mucin‐producing adenocarcinoma of the prostate is a rare disease that includes prostate adenocarcinoma with mucus production, secondary adenocarcinoma from the bladder or colorectum, and adenocarcinoma from the urothelium of the prostatic ...

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Prediction of human pharmacokinetics for low‐clearance compounds using pharmacokinetic data from chimeric mice with humanized livers

Publication Type:Academic Journal

Source(s):Clinical and Translational Science, Vol 15, Iss 1, Pp 79-91 (2022)

Abstract:Abstract Development of low‐clearance (CL) compounds that are slowly metabolized is a major goal in the pharmaceutical industry. However, the pursuit of low intrinsic CL (CLint) often leads to significant challenges in evaluating the pharmacokinetics o...

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Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol

Publication Type:Academic Journal

Source(s):Contemporary Clinical Trials Communications, Vol 29, Iss , Pp 100967- (2022)

Abstract:Background: It is unclear which laxatives are appropriate to prevent opioid-induced constipation (OIC). This study will evaluate whether prophylactic use of naldemedine prevents OIC in patients with cancer who start opioid administration. Methods: This...

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Novel pediatric granulomatosis with polyangiitis with a marked bloody pericardial effusion and bloody stool: a case report

Publication Type:Academic Journal

Source(s):Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-7 (2021)

Abstract:Abstract Background Granulomatosis with polyangiitis (GPA) is a syndrome of refractory vasculitis involving the upper respiratory tract, lungs, kidneys, and systemic small and medium-sized arteries that affects all age groups. No pediatric case with a ...

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The prevalence of artificially administered nutrition and hydration in different age groups among patients with advanced cancer admitted to palliative care units

Publication Type:Academic Journal

Source(s):Clinical Nutrition Open Science, Vol 40, Iss , Pp 69-78 (2021)

Abstract:Summary: Background & Aims: The prevalence of artificially administered nutrition and hydration (AANH) in different age groups among patients with advanced cancer remains unknown. The present study investigated the current utilization of AANH according...

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