Advanced Search Results For "Scheijen JLJM"
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A Citrus and Pomegranate Complex Reduces Methylglyoxal in Healthy Elderly Subjects: Secondary Analysis of a Double-Blind Randomized Cross-Over Clinical Trial.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Aug 24; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 24.
Abstract: Reactive α-dicarbonyls (α-DCs), such as methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), are potent precursors in the formation of advanced glycation end products (AGEs). In particular, MGO and MGO-derived AGEs are thought to be involved...
Effects of fructose added to an oral glucose tolerance test on plasma glucose excursions in healthy adults.
Publication Type: Academic Journal
Source(s): Metabolism open [Metabol Open] 2023 May 12; Vol. 18, pp. 100245. Date of Electronic Publication: 2023 May 12 (Print Publication: 2023).
Abstract: Background and Objective: Previous experimental studies have shown that fructose interacts with glucose metabolism by increasing hepatic glucose uptake. However, human studies investigating the effects of small ('catalytic') amounts of fructose, added ...
Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial.
Publication Type: Academic Journal
Source(s): Diabetes, obesity & metabolism [Diabetes Obes Metab] 2023 May; Vol. 25 (5), pp. 1280-1291. Date of Electronic Publication: 2023 Feb 14.
Abstract: Aim: To investigate the effects of pyridoxamine (PM), a B6 vitamer and dicarbonyl scavenger, on glycation and a large panel of metabolic and vascular measurements in a randomized double-blind placebo-controlled trial in abdominally obese individuals.Ma...
Increased methylglyoxal formation in plasma and tissues during a glucose tolerance test is derived from exogenous glucose.
Publication Type: Academic Journal
Source(s): Clinical science (London, England : 1979) [Clin Sci (Lond)] 2023 Apr 26; Vol. 137 (8), pp. 697-706.
Abstract: The dicarbonyl compound methylglyoxal (MGO) is a major precursor in the formation of advanced glycation endproducts (AGEs). MGO and AGEs are increased in subjects with diabetes and are associated with fatal and nonfatal cardiovascular disease. Previous...
Comment on Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care 2022;45:1917-1930.
Publication Type: Academic Journal
Source(s): Diabetes care [Diabetes Care] 2023 Apr 01; Vol. 46 (4), pp. e97-e98.
The Intake of Dicarbonyls and Advanced Glycation Endproducts as Part of the Habitual Diet Is Not Associated with Intestinal Inflammation in Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients.
Publication Type: Academic Journal
Source(s): Nutrients [Nutrients] 2022 Dec 24; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 24.
Abstract: A Western diet comprises high levels of dicarbonyls and advanced glycation endproducts (AGEs), which may contribute to flares and symptoms in inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We therefore investigated the intake of d...
Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma.
Publication Type: Academic Journal
Source(s): Journal of human hypertension [J Hum Hypertens] 2022 Nov 23. Date of Electronic Publication: 2022 Nov 23.
Abstract: Patients with an aldosterone-producing adenoma (APA) carry a higher risk of cardiovascular disease and commonly have high levels of autoantibodies (AT1AA) that may activate the angiotensin II type 1 receptor (AT1R). AT1R activation is linked to an incr...
Association of α-Dicarbonyls and Advanced Glycation End Products with Insulin Resistance in Non-Diabetic Young Subjects: A Case-Control Study.
Publication Type: Academic Journal
Source(s): Nutrients [Nutrients] 2022 Nov 21; Vol. 14 (22). Date of Electronic Publication: 2022 Nov 21.
Abstract: α-Dicarbonyls and advanced glycation end products (AGEs) may contribute to the pathogenesis of insulin resistance by a variety of mechanisms. To investigate whether young insulin-resistant subjects present markers of increased dicarbonyl stress, we det...
A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 May 10; Vol. 23 (10). Date of Electronic Publication: 2022 May 10.
Abstract: Dietary advanced glycation endproducts (AGEs), abundantly present in Westernized diets, are linked to negative health outcomes, but their impact on the gut microbiota has not yet been well investigated in humans. We investigated the effects of a 4-week...
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
Publication Type: Academic Journal
Source(s): The American journal of clinical nutrition [Am J Clin Nutr] 2022 Jan 11; Vol. 115 (1), pp. 34-44.
Abstract: Background: Dicarbonyls are highly reactive compounds and major precursors of advanced glycation end products (AGEs). Both dicarbonyls and AGEs are associated with development of age-related diseases. Dicarbonyls are formed endogenously but also during...