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Durvalumab after definitive chemoradiotherapy in locally advanced NSCLC: Data of the German EAP
Publication Type: Academic Journal
Source(s): Data in Brief, Vol 34, Iss , Pp 106556- (2021)
Abstract: Following the PACIFIC trial, durvalumab has been approved by the European Medicines Agency (EMA) for consolidation of locally advanced PD-L1-positive NSCLC after chemoradiotherapy (CRT). Patients were treated with durvalumab in the EAP from 22.11.2017 ...
Cardiac Rehabilitation in German Speaking Countries of Europe—Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH—Part 2
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine, Vol 10, Iss 3071, p 3071 (2021)
Abstract: Background: Scientific guidelines have been developed to update and harmonize exercise based cardiac rehabilitation (ebCR) in German speaking countries. Key recommendations for ebCR indications have recently been published in part 1 of this journal. Th...
Comparison of Mechanical Support with Impella or Extracorporeal Life Support in Post-Cardiac Arrest Cardiogenic Shock: A Propensity Scoring Matching Analysis
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine, Vol 10, Iss 3583, p 3583 (2021)
Abstract: Our aim was to compare the outcomes of Impella with extracorporeal life support (ECLS) in patients with post-cardiac arrest cardiogenic shock (CS) complicating acute myocardial infarction (AMI). This was a retrospective study of patients resuscitated f...
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Abstract: Typhoid fever is caused by the bacterium Salmonella Typhi. Here, Park et al. analyse the genomes of 249 S. Typhi isolates from 11 sub-Saharan African countries, identifying genes and plasmids associated with antibiotic resistance and showing that multi...
Left Ventricle Architecture and Valvular Integrity Following Microaxial Mechanical Support: A Two-Year Follow-Up Study
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine, Vol 10, Iss 1273, p 1273 (2021)
Abstract: Although the use of microaxilar mechanical circulatory support systems may improve the outcome of patients with cardiogenic shock (CS), little is known about its effect on the long-term structural integrity of left ventricular (LV) valves as well as on...
Prevalence Estimates for Pharmacological Neuroenhancement in Austrian University Students: Its Relation to Health-Related Risk Attitude and the Framing Effect of Caffeine Tablets
Publication Type: Academic Journal
Source(s): Frontiers in Pharmacology, Vol 9 (2018)
Abstract: Background: Pharmacological neuroenhancement (PN) is defined as the use of illicit or prescription drugs by healthy individuals for cognitive-enhancing purposes. The present study aimed (i) to investigate whether including caffeine tablets in the defin...
The Lipopeptide MALP-2 Promotes Collateral Growth
Publication Type: Academic Journal
Source(s): Cells, Vol 9, Iss 997, p 997 (2020)
Abstract: Beyond their role in pathogen recognition and the initiation of immune defense, Toll-like receptors (TLRs) are known to be involved in various vascular processes in health and disease. We investigated the potential of the lipopeptide and TLR2/6 ligand ...
Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition
Publication Type: Academic Journal
Source(s): Disease Models & Mechanisms, Vol 8, Iss 9, Pp 1071-1080 (2015)
Abstract: Myocardial infarction and stroke are frequent after surgical procedures and consume a considerable amount of benefit of surgical therapy. Perioperative stress, induced by surgery, is composed of hemodynamic and inflammatory reactions. The effects of pe...
Novel manufacturing techniques for microstructured reactors in industrial dimensions
Publication Type: Academic Journal
Source(s): Green Processing and Synthesis, Vol 2, Iss 5, Pp 451-463 (2013)
Abstract: The results of the development of novel manufacturing techniques for microstructured reactors in the framework of the European project CoPIRIDE are reported. The work was aimed at promoting the application of microstructured chemical reactors in the ch...
Ultrafast dynamics of a bi-stable azopyridine Ni-porphyrin spin switch after photoexcitation in the porphyrin B-bands
Publication Type: Academic Journal
Source(s): EPJ Web of Conferences, Vol 205, p 05019 (2019)
Abstract: Femtosecond time-resolved absorption measurements of a magnetically bi-stable azopyridine Ni-porphyrin in solution at room temperature show that the photo-induced dynamics are dominated by transient low-spin ⇄ high-spin interconversion involving Ni (d2...