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JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis
Publication Type: Academic Journal
Source(s): Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract: Abstract Long noncoding RNAs (lncRNAs) are a novel class of noncoding RNAs that have emerged as critical regulators and biomarkers in various cancers. Nevertheless, the expression profile and mechanistic function of lncRNAs in cholangiocarcinoma (CCA) ...
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer
Publication Type: Academic Journal
Source(s): Bioengineered, Vol 13, Iss 5, Pp 13238-13251 (2022)
Abstract: Intratumoral hypoxia is a common feature of pancreatic cancer (PC) and also plays a role in its progression. However, hypoxia-regulated signatures in PC are still not completely understood. This study aimed to identify core hypoxia-associated genes and...
Long noncoding RNA LINC00857 promotes pancreatic cancer proliferation and metastasis by regulating the miR-130b/RHOA axis
Publication Type: Academic Journal
Source(s): Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract: Abstract Dysregulation of long noncoding RNAs (lncRNAs) is involved in the pathogenesis and progression of pancreatic cancer (PC). In the current study, we investigated the role and molecular mechanism of LINC00857 in PC. The expression of LINC00857 in...
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2
Publication Type: Academic Journal
Source(s): Bioengineered, Vol 13, Iss 4, Pp 8643-8656 (2022)
Abstract: Terpinen-4-ol (T4O), a compound isolated from the seeds of turmeric, has exhibited anti-malignancy, anti-aging, and anti-inflammatory properties in previous studies. However, the specific effects and molecular mechanisms of T4O on pancreatic cancer (PC...
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression
Publication Type: Academic Journal
Source(s): Cell Death and Disease, Vol 13, Iss 3, Pp 1-15 (2022)
Abstract: Abstract Dysregulation of autophagy and circular RNAs (circRNAs) are involved in the pancreatic cancer (PC) progression. However, the regulatory network between circRNAs, autophagy, and PC progression remains unknown. Herein, we demonstrated that autop...
Hypoxia-Related Gene FUT11 Promotes Pancreatic Cancer Progression by Maintaining the Stability of PDK1
Publication Type: Academic Journal
Source(s): Frontiers in Oncology, Vol 11 (2021)
Abstract: BackgroundHypoxia is associated with the development of pancreatic cancer (PC). However, genes associated with hypoxia response and their regulatory mechanism in PC cells were unclear. The current study aims to investigate the role of the hypoxia assoc...
Influence of Entanglements on Ultrahigh Strain Rate Deformation of Polystyrene Microprojectiles.
Publication Type: Academic Journal
Source(s): Macromolecules; 11/8/2022, Vol. 55 Issue 21, p9594-9600, 7p
Layered Thin Film Deposition via Extreme Inter-Brush Slip in a Lamellar Block Copolymer.
Publication Type: Academic Journal
Source(s): Macromolecules; 10/25/2022, Vol. 55 Issue 20, p9022-9029, 8p
Efficient lung cancer-targeted drug delivery via a nanoparticle/MSC system
Publication Type: Academic Journal
Source(s): Acta Pharmaceutica Sinica B, Vol 9, Iss 1, Pp 167-176 (2019)
Abstract: Low targeting efficiency limits the applications of nanoparticles in cancer therapy. The fact that mesenchymal stem cells (MSC) trapped in the lung after systemic infusion is a disadvantage for cell therapy purposes. Here, we utilized MSC as lung cance...
Fine-tuned order-order phase transitions in giant surfactants via interfacial engineering
Publication Type: Academic Journal
Source(s): Giant, Vol 1, Iss , Pp 100002- (2020)
Abstract: Thermotropic order-order phase transitions (OOTs) in block copolymers are not commonly observed in the strong segregation region. Phase separation of giant surfactants composed of hydrophilic molecular nanoparticles (MNPs) as heads and hydrophobic flex...