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Advanced Search Results For "Shannon, Elaine"

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 "Shannon, Elaine"
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Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)

Abstract: Abstract Single-cell assays have enriched our understanding of hematopoiesis and, more generally, stem and progenitor cell biology. However, these single-end-point approaches provide only a static snapshot of the state of a cell. To observe and measure...

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Separate and combined effects of advanced age and obesity on mammary adipose inflammation, immunosuppression and tumor progression in mouse models of triple negative breast cancer

Publication Type: Academic Journal

Source(s): Frontiers in Oncology, Vol 12 (2023)

Abstract: IntroductionAdvanced age and obesity are independent risk and progression factors for triple negative breast cancer (TNBC), which presents significant public health concerns for the aging population and its increasing burden of obesity. Due to parallel...

R2Play development: Fostering user-driven technology that supports return-to-play decision-making following pediatric concussion

Publication Type: Academic Journal

Source(s): Frontiers in Rehabilitation Sciences, Vol 3 (2022)

Abstract: ObjectiveTo design a multi-domain return-to-play assessment system (R2Play) for youth athletes with concussion.MethodsThe R2Play system was developed using an overarching user-centered approach, the Design Thinking Framework, and research activities in...

A survey of food-borne and antimicrobial resistance-harbouring bacteria in meat by-products from knackeries and associated equipment and kennels

Publication Type: Academic Journal

Source(s): Irish Veterinary Journal, Vol 75, Iss 1, Pp 1-8 (2022)

Abstract: Abstract Background In Ireland, meat by-products (MBP) harvested at knackeries from farmed animals that have not died of an infectious or systemic disease are legally permitted to be fed to dogs in kennels and packs of hounds. There is limited informat...

NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats

Publication Type: Academic Journal

Source(s): eLife, Vol 11 (2022)

Abstract: NBI-921352 (formerly XEN901) is a novel sodium channel inhibitor designed to specifically target NaV1.6 channels. Such a molecule provides a precision-medicine approach to target SCN8A-related epilepsy syndromes (SCN8A-RES), where gain-of-function (GoF...

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Abstract: Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality. Here, the authors analyse whole genome sequence data and find new loci associated with lung function and COPD.

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A pilot study using environmental screening to determine the prevalence of Mycobacterium avium subspecies paratuberculosis (MAP) and antimicrobial resistance (AMR) in Irish cattle herds

Publication Type: Academic Journal

Source(s): Irish Veterinary Journal, Vol 73, Iss 1, Pp 1-11 (2020)

Abstract: Abstract Background Dairy and beef cattle can be reservoirs of many pathogens, including Salmonella and Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne’s disease (JD). Farm environments may provide potential entry points...

Evaluating Full Day Kindergarten – Is It Associated with Improved Short- And Long-Term Education Outcomes Among Metis Children?

Publication Type: Academic Journal

Source(s): International Journal of Population Data Science, Vol 5, Iss 5 (2020)

Abstract: Introduction Early education outcomes influence children’s educational trajectories with long-term effects extending into adulthood. Aboriginal peoples face numerous systemic barriers to academic success. It remains unknown if full-day kindergarten (FD...

Evaluation of The Manitoba Healthy Baby Prenatal Benefit: Is It Improving Birth and Early Childhood Outcomes for Metis Families?

Publication Type: Academic Journal

Source(s): International Journal of Population Data Science, Vol 5, Iss 5 (2020)

Abstract: Introduction In Manitoba, low-income pregnant women are eligible for the Healthy Baby Prenatal Benefit (HBPB), a prenatal income supplement. Research has demonstrated positive outcomes associated with HBPB, but it remains unknown if Metis women and chi...

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