Advanced Search Results For "Sim, Leslie"

Publication Type: Academic Journal

Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)

Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...

Publication Type: Academic Journal

Source(s): Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)

Abstract: A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Publication Type: Academic Journal

Source(s): Cancers, Vol 15, Iss 1024, p 1024 (2023)

Abstract: Patient-reported outcome measures (PROMs) are subjective assessments of health status or health-related quality of life. In childhood cancer survivors, PROMs can be used to evaluate the adverse effects of cancer treatment and guide cancer survivorship ...

Publication Type: Academic Journal

Source(s): International Journal for Equity in Health, Vol 21, Iss 1, Pp 1-14 (2022)

Abstract: Abstract Background An Aboriginal-developed empowerment and social and emotional wellbeing program, known as Family Wellbeing (FWB), has been found to strengthen the protective factors that help Indigenous Australians to deal with the legacy of colonis...

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Abstract: Penetrance of variants in monogenic disease and clinical utility of common polygenic variation has not been well explored on a large-scale. Here, the authors use exome sequencing data from 77,184 individuals to generate penetrance estimates and assess ...

Publication Type: Academic Journal

Source(s): Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)

Abstract: Abstract Background It is well-established that cancer treatment substantially increases the risk of long-term adverse health outcomes among childhood cancer survivors. However, there is limited research on the underlying mechanisms. To elucidate the p...

Publication Type: Academic Journal

Source(s): Journal of Eating Disorders, Vol 9, Iss 1, Pp 1-10 (2021)

Abstract: Plain English summary Family-Based Treatment (FBT) is considered the first-choice intervention for adolescent anorexia nervosa. However, finding a qualified provider in this modality is difficult. Treatment programs for other pediatric mental health co...

Publication Type: Academic Journal

Source(s): Journal of Eating Disorders, Vol 9, Iss 1, Pp 1-8 (2021)

Abstract: Abstract Background The primary care setting offers an attractive opportunity for, not only the identification of pediatric eating disorders, but also the delivery of evidence-based treatment. However, constraints of this setting pose barriers for impl...

Publication Type: Academic Journal

Source(s): Journal of Developmental & Behavioral Pediatrics; May2023, Vol. 44 Issue 4, pe277-e283, 7p

Publication Type: Academic Journal

Source(s): Critical Care Explorations, Vol 3, Iss 11, p e0567 (2021)

Abstract: IMPORTANCE:. Factors associated with mortality in coronavirus disease 2019 patients on invasive mechanical ventilation are still not fully elucidated. OBJECTIVES:. To identify patient-level parameters, readily available at the bedside, associated with ...