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Advanced Search Results For "Song, Miranda"

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 "Song, Miranda"
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Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application

Publication Type:Academic Journal

Source(s):Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-52 (2022)

Abstract:Abstract Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive cognitive impairment and neurodegeneration. Extensive clinical and genomic studies have revealed biomarkers, risk factors, pathways, and targets of AD i...

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Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance

Publication Type:Academic Journal

Source(s):Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)

Abstract:Ottilie et al. employ an experimental evolution approach to investigate the role of transcription factors in yeast chemical resistance. Most emergent mutations in resistant strains were enriched in transcription factor coding genes, highlighting their ...

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The landscape of human tissue and cell type specific expression and co-regulation of senescence genes

Publication Type:Academic Journal

Source(s):Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-20 (2022)

Abstract:Abstract Background Cellular senescence is a complex stress response that impacts cellular function and organismal health. Multiple developmental and environmental factors, such as intrinsic cellular cues, radiation, oxidative stress, oncogenes, and pr...

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Stroke care and collaborative academic research in Latin America

Publication Type:Academic Journal

Source(s):Salud Pública de México, Vol 64, Pp S40-S45 (2022)

Abstract:Objective. A narrative overview of regional academic research collaborations to address the increasing burden and gaps in care for patients at risk of, and who suffer from, stroke in Latin America (LA). Materials and methods. A summary of experiences a...

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SEPIA: simulation-based evaluation of prioritization algorithms

Publication Type:Academic Journal

Source(s):BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-5 (2021)

Abstract:Abstract Background The ability to prioritize people living with HIV (PLWH) by risk of future transmissions could aid public health officials in optimizing epidemiological intervention. While methods exist to perform such prioritization based on molecu...

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Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients

Publication Type:Academic Journal

Source(s):Frontiers in Immunology, Vol 11 (2020)

Abstract:Severe COVID-19 is associated with profound lymphopenia and an elevated neutrophil to lymphocyte ratio. We applied a novel dimer avoidance multiplexed polymerase chain reaction next-generation sequencing assay to analyze T (TCR) and B cell receptor (BC...

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High throughput sequencing of T-cell receptor repertoire using dry blood spots

Publication Type:Academic Journal

Source(s):Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)

Abstract:Abstract Background Immunology research, particularly next generation sequencing (NGS) of the immune T-cell receptor β (TCRβ) repertoire, has advanced progression in several fields, including treatment of various cancers and autoimmune diseases. This s...

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