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Advanced Search Results For "Steiger RL"

1 - 10 of 33 results for
 "Steiger RL"
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The association between perceived community violence, police bias, race, and firearm carriage among urban adolescents and young adults.

Publication Type:Academic Journal

Source(s):Preventive medicine [Prev Med] 2022 Jan; Vol. 154, pp. 106897. Date of Electronic Publication: 2021 Dec 01.

Abstract:Firearms are a leading cause of death among youth and young adults. Given community violence is an important correlate of youth firearm carriage, we evaluated: 1) If the association between perceived community violence and firearm carriage is stronger ...

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Surgical treatment of brainstem cavernous malformations: an international Delphi consensus.

Publication Type:Academic Journal

Source(s):Journal of neurosurgery [J Neurosurg] 2021 Oct 01, pp. 1-11. Date of Electronic Publication: 2021 Oct 01.

Abstract:Objective: Indication for surgery in brainstem cavernous malformations (BSCMs) is based on many case series, few comparative studies, and no randomized controlled trials. The objective of this study was to seek consensus about surgical management aspec...

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LGBT workplace protections as an extension of the protected class framework.

Publication Type:Academic Journal

Source(s):Law and human behavior [Law Hum Behav] 2020 Aug; Vol. 44 (4), pp. 251-265.

Abstract:Objectives: Many corporations in the United States have enacted nondiscrimination policies for their LGBT employees, despite that the LGBT community has not been a legally protected class concerning employment discrimination at the national level. We e...

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Nimodipine pharmacokinetics after intraventricular injection of sustained-release nimodipine for subarachnoid hemorrhage.

Publication Type:Academic Journal

Source(s):Journal of neurosurgery [J Neurosurg] 2019 Dec 06, pp. 1-7. Date of Electronic Publication: 2019 Dec 06.

Abstract:Objective: The objective of this study was to measure the concentration of nimodipine in CSF and plasma after intraventricular injection of a sustained-release formulation of nimodipine (EG-1962) in patients with aneurysmal subarachnoid hemorrhage (SAH...

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Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes.

Publication Type:Academic Journal

Source(s):Hepatology (Baltimore, Md.) [Hepatology] 2018 Dec; Vol. 68 (6), pp. 2089-2105. Date of Electronic Publication: 2018 Sep 27.

Abstract:The liver bears unique immune properties that support both immune tolerance and immunity, but the mechanisms responsible for clearance versus persistence of virus-infected hepatocytes remain unclear. Here, we dissect the factors determining the outcome...

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Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).

Publication Type:Academic Journal

Source(s):Stroke [Stroke] 2017 Jan; Vol. 48 (1), pp. 145-151. Date of Electronic Publication: 2016 Dec 08.

Abstract:Background and Purpose: We conducted a randomized, open-label, phase 1/2a, dose-escalation study of intraventricular sustained-release nimodipine (EG-1962) to determine safety, tolerability, pharmacokinetics, and clinical effects in aneurysmal subarach...

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Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model.

Publication Type:Academic Journal

Source(s):The American journal of pathology [Am J Pathol] 2016 Nov; Vol. 186 (11), pp. 2934-2944. Date of Electronic Publication: 2016 Sep 14.

Abstract:Perturbation of pancreatic acinar cell state can lead to acinar-to-ductal metaplasia (ADM), a precursor lesion to the development of pancreatic ductal adenocarcinoma (PDAC). In the pancreas, Notch signaling is active both during development and in adul...

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Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages.

Publication Type:Academic Journal

Source(s):Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Jul 01; Vol. 197 (1), pp. 222-32. Date of Electronic Publication: 2016 May 27.

Abstract:Glucocorticoids are extensively used to treat inflammatory diseases; however, their chronic intake increases the risk for mycobacterial infections. Meanwhile, the effects of glucocorticoids on innate host responses are incompletely understood. In this ...

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A Site-Specific, Sustained-Release Drug Delivery System for Aneurysmal Subarachnoid Hemorrhage.

Publication Type:Academic Journal

Source(s):Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2016 Apr; Vol. 13 (2), pp. 439-49.

Abstract:Nimodipine is the only drug approved for use by the Food and Drug Administration for improving outcome after aneurysmal subarachnoid hemorrhage (SAH). It has less than optimal efficacy, causes dose-limiting hypotension in a substantial proportion of pa...

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NEWTON: Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage.

Publication Type:Academic Journal

Source(s):Neurocritical care [Neurocrit Care] 2015 Oct; Vol. 23 (2), pp. 274-84.

Abstract:Background: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high morbidity and mortality. EG-1962 is a sustained-release microparticle formulation of nimodipine that has shown preclinical efficacy when administered intraventricularly or in...

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