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SARS-CoV-2 Vaccination and Clinical Presentation of COVID-19 in Patients Hospitalized during the Delta- and Omicron-Predominant Periods

Publication Type: Academic Journal

Source(s): Journal of Clinical Medicine, Vol 12, Iss 961, p 961 (2023)

Abstract: Evidence suggests that monovalent vaccine formulations are less effective against the Omicron SARS-CoV-2 than against previous variants. In this retrospective cohort study of hospitalized adults with PCR-confirmed COVID-19 during the Delta (October–Nov...

SARS-CoV-2 Vaccination and Clinical Presentation of COVID-19 in Patients Hospitalized during the Delta- and Omicron-Predominant Periods.

Publication Type: Academic Journal

Source(s): Journal of Clinical Medicine. Feb2023, Vol. 12 Issue 3, p961. 13p.

Abstract: Evidence suggests that monovalent vaccine formulations are less effective against the Omicron SARS-CoV-2 than against previous variants. In this retrospective cohort study of hospitalized adults with PCR-confirmed COVID-19 during the Delta (October–Nov...

Systemic immune responses in patients with early localized or early disseminated Borrelia afzelii lyme borreliosis

Publication Type: Academic Journal

Source(s): Immunity, Inflammation and Disease, Vol 9, Iss 2, Pp 375-387 (2021)

Abstract: Abstract Introduction The role of host immune responses in the pathogenesis of borrelial dissemination in early Lyme borreliosis (LB) in the form of multiple erythema migrans (MEM) or LB‐associated symptoms is incompletely understood. Methods In this s...

The Impact of SARS-CoV-2 Primary Vaccination in a Cohort of Patients Hospitalized for Acute COVID-19 during Delta Variant Predominance

Publication Type: Academic Journal

Source(s): Journal of Clinical Medicine, Vol 11, Iss 1191, p 1191 (2022)

Abstract: Vaccine breakthrough SARS-CoV-2 infections necessitating hospitalization have emerged as a relevant problem with longer time interval since vaccination and the predominance of the Delta variant. The aim of this study was to evaluate the association bet...

Association between statin use and clinical course, microbiologic characteristics, and long-term outcome of early Lyme borreliosis. A post hoc analysis of prospective clinical trials of adult patients with erythema migrans.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 16, Iss 12, p e0261194 (2021)

Abstract: BackgroundStatins were shown to inhibit borrelial growth in vitro and promote clearance of spirochetes in a murine model of Lyme borreliosis (LB). We investigated the impact of statin use in patients with early LB.MethodsIn this post-hoc analysis, the ...

Subjects:

Doxycycline-induced photosensitivity in patients treated for erythema migrans

Publication Type: Academic Journal

Source(s): BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-5 (2018)

Abstract: Abstract Background Doxycycline is one of the recommended antibiotics for treating erythema migrans (EM). Since EM predominantly occurs during summer, the potential of doxycycline to induce photosensitivity is of concern. In studies on the efficacy of ...

Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trial.

Publication Type: Academic Journal

Source(s): Lancet Infectious Diseases. Mar2023, Vol. 23 Issue 3, p371-379. 9p.

Abstract: Lyme borreliosis is the most prevalent vector-borne disease in Europe and the USA. Doxycycline for 10 days is the primary treatment recommendation for erythema migrans. To reduce potentially harmful antibiotic overuse by identifying shorter effective t...

Impact of pre-existing treatment with statins on the course and outcome of tick-borne encephalitis.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 13, Iss 10, p e0204773 (2018)

Abstract: OBJECTIVES:Although statins have anti-inflammatory and potentially also antimicrobial (including antiviral) activity, their therapeutic impact on infectious diseases is controversial. In this study, we evaluated whether pre-existing statin use influenc...

Subjects:

Antibiotic Use and Long-Term Outcome in Patients with Tick-Borne Encephalitis and Co-Infection with Borrelia Burgdorferi Sensu Lato in Central Europe. A Retrospective Cohort Study

Publication Type: Academic Journal

Source(s): Journal of Clinical Medicine, Vol 8, Iss 10, p 1740 (2019)

Abstract: In this retrospective cohort study of patients with tick-borne encephalitis (TBE), the clinical outcome in relation to co-infection with B. burgdorferi sensu lato (s.l.) and, specifically, the effect of antibiotic treatment on clinical outcome in patie...

Clinical Course, Serologic Response, and Long-Term Outcome in Elderly Patients with Early Lyme Borreliosis

Publication Type: Academic Journal

Source(s): Journal of Clinical Medicine, Vol 7, Iss 12, p 506 (2018)

Abstract: Infected elderly people often present with signs and symptoms that differ from those in younger adults, but data on the association between patient age and presentation of early Lyme borreliosis (LB) are limited. In this study, the association between ...

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